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Literature DB >> 6615190

Protein pattern of cerebrospinal fluid in various neurological diseases.

Abstract

CSF/serum albumin and immunoglobulin G ratios were determined in 520 patients suffering from various neurological diseases. Blood-brain barrier impairment was detectable in most cases of spinal tumour, meningitis, Guillain-Barré syndrome and in two-thirds of the patients with cerebral infarctions. A local IgG formation in the CNS has to be assumed for some cases of meningitis considering the course of the protein dysequilibrium. Autochthonous IgG production together with a barrier dysfunction was found in patients with encephalitis, meningoradiculitis and neurosyphilis. In cases of multiple sclerosis local IgG formation in the CNS was the predominant finding.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 1983 PMID： 6615190 DOI： 10.1007/bf00343600

Source DB: PubMed Journal: Arch Psychiatr Nervenkr (1970)

15 in total

1. Circulating demyelinating factors in acute idiopathic polyneuropathy.

Authors: S D Cook; P C Dowling; M R Murray; J N Whitaker
Journal: Arch Neurol Date: 1971-02

2. The discrimination between different blood-CSF barrier dysfunctions and inflammatory reactions of the CNS by a recent evaluation graph for the protein profile of cerebrospinal fluid.

Authors: H Reiber
Journal: J Neurol Date: 1980 Impact factor: 4.849

3. The clinical effect and the effect on serum IgG antibodies to peripheral nerve tissue of plasma exchange in patients wit Guillain-Barré syndrome.

Authors: C A Vedeler; H Nyland; J Fagius; P O Osterman; R Matre; J A Aarli; R W Janzen; H Jacobsen; H Skre
Journal: J Neurol Date: 1982 Impact factor: 4.849

4. Evaluation of the blood-CSF barrier by protein gradients and the humoral immune response within the central nervous system.

Authors: K Felgenhauer; G Schliep; N Rapic
Journal: J Neurol Sci Date: 1976-11 Impact factor: 3.181

9. Pleocytosis and immunoglobulin changes in cerebrospinal fluid and herpesvirus serology in patients with Guillain-Barré syndrome.

Authors: H Link; B Wahren; E Norrby
Journal: J Clin Microbiol Date: 1979-03 Impact factor: 5.948

10. Antimyelin antibodies in neurologic diseases. Immunofluorescent demonstration.

Authors: R P Lisak; B Zwiman; M Norman
Journal: Arch Neurol Date: 1975-03

1 in total

1. Clinical significance of serum and CSF findings in the Guillain-Barré syndrome and related disorders.

Authors: O G Segurado; H Krüger; H G Mertens
Journal: J Neurol Date: 1986-08 Impact factor: 4.849

1 in total

Protein pattern of cerebrospinal fluid in various neurological diseases.

1. Circulating demyelinating factors in acute idiopathic polyneuropathy.

2. The discrimination between different blood-CSF barrier dysfunctions and inflammatory reactions of the CNS by a recent evaluation graph for the protein profile of cerebrospinal fluid.

3. The clinical effect and the effect on serum IgG antibodies to peripheral nerve tissue of plasma exchange in patients wit Guillain-Barré syndrome.

4. Evaluation of the blood-CSF barrier by protein gradients and the humoral immune response within the central nervous system.

5. Relative concentrations of albumin and IgG in cerebrospinal fluid in health and in acute meningitis.

6. Guillain-Barré syndrome: demonstration of antibodies to peripheral nerve tissue.

7. Measurement of IgG and albumin content of cerebrospinal fluid, and its interpretation.

8. Gel isoelectric focusing of cerebrospinal fluid proteins: a potential diagnostic tool.

9. Pleocytosis and immunoglobulin changes in cerebrospinal fluid and herpesvirus serology in patients with Guillain-Barré syndrome.

10. Antimyelin antibodies in neurologic diseases. Immunofluorescent demonstration.

1. Clinical significance of serum and CSF findings in the Guillain-Barré syndrome and related disorders.