Literature DB >> 661518

Prostaglandin metabolism by human testis.

M P Carpenter, R D Robinson, L P Thuy.   

Abstract

Human testis preparations appear to carry out both the synthesis and turnover of prostaglandins. Prostaglandins and prostaglandin metabolites were extracted from whole tissue. Testis microsomes converted both endogenous and exogenous substrate to prostaglandins. Microsomal prostaglandin biosynthesis was inhibited by indomethacin. Prostaglandin E2-9-ketoreductase was present in both the cytosolic and microsomal fractions of human testis. Prostaglandin metabolism by human testis has not previously been reported.

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Year:  1978        PMID: 661518     DOI: 10.1007/BF02533678

Source DB:  PubMed          Journal:  Lipids        ISSN: 0024-4201            Impact factor:   1.880


  9 in total

1.  Biosynthesis of prostaglandin E1 by human seminal vesicles.

Authors:  M Hamberg
Journal:  Lipids       Date:  1976-03       Impact factor: 1.880

2.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

3.  Prostaglandins of rat testis.

Authors:  M P Carpenter
Journal:  Lipids       Date:  1974-06       Impact factor: 1.880

4.  Lipids of human testes removed at orchidectomy.

Authors:  J G Coniglio; W M Grogan; R K Rhamy
Journal:  J Reprod Fertil       Date:  1974-11

5.  Evidence for the presence of a prostaglandin E 2 -9-keto reductase in rat organs.

Authors:  C A Leslie; L Levine
Journal:  Biochem Biophys Res Commun       Date:  1973-06-08       Impact factor: 3.575

6.  Identification of some polyenoic acids isolated from human testicular tissue.

Authors:  W M Grogan; J G Coniglio; R K Rhamy
Journal:  Lipids       Date:  1973-08       Impact factor: 1.880

7.  Ovulation blockade by aspirin or indomethacin--in vivo evidence for a role of prostaglandin in gonadotrophin secretion.

Authors:  G P Orczyk; H R Behrman
Journal:  Prostaglandins       Date:  1972-01

8.  Prostaglandins in human seminal plasma. Prostaglandins and related factors 46.

Authors:  M Hamberg; B Samuelsson
Journal:  J Biol Chem       Date:  1966-01-25       Impact factor: 5.157

9.  Changes in phospholipids of ram spermatozoa during migration through the epididymis and possible origin of prostaglandin F2alpha in testicular and epididymal fluid.

Authors:  A Poulos; P D Brown-Woodman; I G White; R I Cox
Journal:  Biochim Biophys Acta       Date:  1975-04-18
  9 in total
  2 in total

1.  Sertoli-cell prostaglandin synthesis. Effects of (follitropin) differentiation and dietary vitamin E.

Authors:  D R Cooper; M P Carpenter
Journal:  Biochem J       Date:  1987-02-01       Impact factor: 3.857

2.  Role of seminal prostaglandins in male fertility. II. Effects of prostaglandin synthesis inhibition on spermatogenesis in man.

Authors:  D Conte; M Nordio; F Romanelli; F Manganelli; P Giovenco; F Dondero; A Isidori
Journal:  J Endocrinol Invest       Date:  1985-08       Impact factor: 4.256

  2 in total

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