| Literature DB >> 6613525 |
Abstract
The anti-epileptic effect of gamma-vinyl-GABA (GVG) was studied using a placebo-controlled, single-blind design in 15 patients with therapy-resistant epilepsy, the majority experiencing complex partial seizures. GVG was added to concomitant treatment, which was kept at constant serum levels. Following administration of 1 g, 2 g and 3 g per day, significant reductions in seizure frequency were observed. A poor correlation was found between GVG serum levels and clinical effect. Only mild and transient side-effects were observed.Entities:
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Year: 1983 PMID： 6613525 DOI： 10.1111/j.1600-0404.1983.tb04812.x
Source DB: PubMed Journal: Acta Neurol Scand ISSN： 0001-6314 Impact factor: 3.209