Literature DB >> 6612346

Stress-induced suppression of immunity in adrenalectomized rats.

S E Keller, J M Weiss, S J Schleifer, N E Miller, M Stein.   

Abstract

Stress-induced suppression of lymphocyte stimulation by phytohemagglutinin was demonstrated in Isolated lymphocytes and in cultures of whole blood from adrenalectomized rats. The results demonstrate that corticosteroid independent mechanisms participate in the suppression of lymphocyte function by stressors. Stress-induced lymphopenia, however, was found to be adrenal dependent, indicating that the modulation of immunity by stress is complex and multidetermined.

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Year:  1983        PMID： 6612346     DOI： 10.1126/science.6612346

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  24 in total

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