| Literature DB >> 6611605 |
D Bourel, R Fauchet, A M Chevrinais, G Dejour, G Merdrignac, B Genetet.
Abstract
An anti-HLA-A2 and -A28 monoclonal antibody, XV.17, has been prepared by immunizing a Balb/c mouse with PBL. This XV.17 monoclonal antibody is a cytotoxic IgM. Its reactivity was tested by lymphocytotoxicity test and indirect immunofluorescence technique, in parallel with an alloantiserum ORA having the same anti-HLA-A2, -A28 reactivity pattern, against different panels. Family studies were undertaken. Absorptions-elutions and cytofluorometry experiments were performed to study the cross-reaction. The XV.17 monoclonal antibody is cytotoxic against all the HLA-A2 and -A28 tested cells, and is absorbed by HLA-Aw23 and -Aw24 cell suspensions.Entities:
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Year: 1984 PMID： 6611605 DOI： 10.1111/j.1399-0039.1984.tb00045.x
Source DB: PubMed Journal: Tissue Antigens ISSN： 0001-2815