Literature DB >> 6611156

Stimulation of plasminogen activator in osteoblast-like cells by bone-resorbing hormones.

J A Hamilton, S R Lingelbach, N C Partridge, T J Martin.   

Abstract

Hormonal control of plasminogen activator (PA) was studied in clonal rat osteogenic sarcoma cells which are phenotypically osteoblast, and in osteoblast-rich rat bone cell cultures. The bone-resorbing hormones (parathyroid hormone, prostaglandin E2, epidermal growth factor and 1,25-dihydroxyvitamin D3) stimulated PA activity in both cell types. The relative efficacies of vitamin D metabolites and of prostanoids reflect their relative potencies as stimulators of bone resorption.

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Year:  1984        PMID： 6611156     DOI： 10.1016/0006-291x(84)90464-9

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  11 in total

1.  Osteoblast low-molecular-weight proteinase inhibitor. I. Isolation and characterization of activity from osteoblastic cells and bone.

Authors:  F H Wezeman; J Corey; B Waxler
Journal:  Calcif Tissue Int       Date:  1990-04       Impact factor: 4.333

2.  Regulation of plasminogen activator and plasminogen activator inhibitor production by growth factors and cytokines in rat calvarial cells.

Authors:  S L Cheng; V Shen; W A Peck
Journal:  Calcif Tissue Int       Date:  1991-11       Impact factor: 4.333

Review 3.  The pathobiology of the osteoclast.

Authors:  T J Chambers
Journal:  J Clin Pathol       Date:  1985-03       Impact factor: 3.411

4.  Bisphosphonates inhibit 1,25-dihydroxyvitamin D3-induced increase of osteocalcin in plasma of rats in vivo and in culture medium of rat calvaria in vitro.

Authors:  S A Stronski; L Bettschen-Camin; A Wetterwald; R Felix; U Trechsel; H Fleisch
Journal:  Calcif Tissue Int       Date:  1988-04       Impact factor: 4.333

Review 5.  Hormones in the coupling of bone resorption and formation.

Authors:  T J Martin
Journal:  Osteoporos Int       Date:  1993       Impact factor: 4.507

6.  Complement and the recruitment of mononuclear osteoclasts.

Authors:  D C Mangham; D J Scoones; M T Drayson
Journal:  J Clin Pathol       Date:  1993-06       Impact factor: 3.411

7.  Bacterial antigens induce collagenase and prostaglandin E2 synthesis in human gingival fibroblasts through a primary effect on circulating mononuclear cells.

Authors:  J K Heath; S J Atkinson; R M Hembry; J J Reynolds; M C Meikle
Journal:  Infect Immun       Date:  1987-09       Impact factor: 3.441

8.  Partial inhibition of bone resorption by disodium cromoglycate in a synchronized model of bone remodeling.

Authors:  C Dobigny; J L Saffar
Journal:  Agents Actions       Date:  1991-07

9.  Modulation of proteases and their inhibitors in immortal human osteoblast-like cells by tumor necrosis factor-alpha in vitro.

Authors:  F S Panagakos; S Kumar
Journal:  Inflammation       Date:  1994-06       Impact factor: 4.092

10.  The urokinase plasminogen activator (u-PA) and its inhibitor (PAI-1) in embryo-fetal bone formation in the human: an immunohistochemical study.

Authors:  C Häckel; K Radig; I Röse; A Roessner
Journal:  Anat Embryol (Berl)       Date:  1995-10
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