Literature DB >> 6611131

Assessment of dopamine receptor densities in the human brain with carbon-11-labeled N-methylspiperone.

H N Wagner, H D Burns, R F Dannals, D F Wong, B Langström, T Duelfer, J J Frost, H T Ravert, J M Links, S B Rosenbloom.   

Abstract

We describe the use of carbon-11-labeled 3-N-methylspiperone, a ligand that preferentially binds to dopamine receptors in vivo, to image the receptors by positron emission tomography scanning in baboons and, for the first time, in a human. The method has now been used in 58 humans for noninvasive assessment of the state of brain dopamine receptors under normal and pathological conditions.

Entities:  

Mesh：

Substances：

Year:  1984        PMID： 6611131     DOI： 10.1002/ana.410150715

Source DB:  PubMed          Journal:  Ann Neurol        ISSN： 0364-5134            Impact factor:   10.422


  4 in total

Review 1.  Neuroimaging, genetics and the treatment of nicotine addiction.

Authors:  Riju Ray; James Loughead; Ze Wang; John Detre; Edward Yang; Ruben Gur; Caryn Lerman
Journal:  Behav Brain Res       Date:  2008-06-05       Impact factor: 3.332

2.  Absorbed fractions for dose calculations of neuroreceptor PET studies.

Authors:  A N Bice; J M Links; D F Wong; H N Wagner
Journal:  Eur J Nucl Med       Date:  1985

3.  Evaluation of 75Br-labelled butyrophenone neuroleptics for imaging cerebral dopaminergic receptor areas using positron emission tomography.

Authors:  S M Moerlein; P Laufer; G Stöcklin; G Pawlik; K Wienhard; W D Heiss
Journal:  Eur J Nucl Med       Date:  1986

Review 4.  Allosteric Interactions between Adenosine A2A and Dopamine D2 Receptors in Heteromeric Complexes: Biochemical and Pharmacological Characteristics, and Opportunities for PET Imaging.

Authors:  Kavya Prasad; Erik F J de Vries; Philip H Elsinga; Rudi A J O Dierckx; Aren van Waarde
Journal:  Int J Mol Sci       Date:  2021-02-09       Impact factor: 5.923
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.