Literature DB >> 6609797

Purification of human alpha 1 antiprotease-pancreatic elastase complex. Interaction with homologous elastin.

M Rabaud, P Dabadie, F Lefebvre, C Desgranges, H Bricaud.   

Abstract

A human alpha 1-antiprotease (alpha 1.AP)-human pancreatic elastase ( HPE11 ) complex was isolated from plasma, or prepared from commercial alpha 1.AP. The complex was identified and isolated by affinity chromatography, using Concanavalin A or IgG anti-elastase as ligands, in association with Sephacryl gel filtration. The alpha 1.AP- HPE11 complex was shown to bind with aorta and with purified aortic elastin. In both cases, the complex exhibited elastinolytic activity.

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Year:  1984        PMID： 6609797     DOI： 10.3109/03008208408992781

Source DB:  PubMed          Journal:  Connect Tissue Res        ISSN： 0300-8207            Impact factor:   3.417


  5 in total

1.  Inhibition of human pancreatic elastase II activity on human aortic elastin by human alpha 2-macroglobulin.

Authors:  J Graveline; M Garret; L Zourgui; P Lambin; F Lefebvre; M Rabaud
Journal:  Experientia       Date:  1986-07-15

2.  Collagen studies in congenital cutis laxa.

Authors:  A Taïeb; M Aumailley; D Courouge-Dorcier; M Rabaud; P Bioulac-Sage; J E Surlève-Bazeille; J Maleville
Journal:  Arch Dermatol Res       Date:  1987       Impact factor: 3.017

3.  Kinetics of the inhibition of human pancreatic elastase by recombinant eglin c. Influence of elastin.

Authors:  B Faller; S Dirrig; M Rabaud; J G Bieth
Journal:  Biochem J       Date:  1990-09-15       Impact factor: 3.857

4.  Subcellular localization and further characterization of a new elastase inhibitor from pneumococci.

Authors:  M Vered; S R Simon; A Janoff
Journal:  Infect Immun       Date:  1985-07       Impact factor: 3.441

5.  The circulating alpha 1-antitrypsin-elastase complex attacks the elastic lamina of blood vessels. An immunohistochemical study.

Authors:  T Tsujii; K Katayama; I Naito; S Seno
Journal:  Histochemistry       Date:  1988
  5 in total

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