| Literature DB >> 6608148 |
W C Eckelman, R C Reba, W J Rzeszotarski, R E Gibson, T Hill, B L Holman, T Budinger, J J Conklin, R Eng, M P Grissom.
Abstract
A radioiodinated ligand that binds to muscarinic acetylcholine receptors was shown to distribute in the brain by a receptor-mediated process. With single-photon-emission imaging techniques, radioactivity was detected in the cerebrum but not in the cerebellum, whereas with a flow-limited radiotracer, radioactivity was detected in cerebrum and cerebellum. Single-photon-emission computed tomography showed good definition of the caudate putamen and cortex in man.Entities:
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Year: 1984 PMID： 6608148 DOI： 10.1126/science.6608148
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728