Literature DB >> 6607894

Gingival hyperplasia caused by nifedipine--a preliminary report.

Y Ramon, S Behar, Y Kishon, I S Engelberg.   

Abstract

We observed marked gingival hyperplasia, similar clinically and histologically to the hyperplasia caused by 5:5 sodium diphenylhydantoin (Dilantin) during the last 18 months in five patients treated by nifedipine. Histologically, marked epithelial hyperplasia-acanthosis, with moderate inflammatory reaction in the lamina propria, was observed in all the biopsy specimens. Evidence points to a strong relationship between the gingival hyperplasia and the administration of nifedipine.

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Year:  1984        PMID： 6607894     DOI： 10.1016/0167-5273(84)90145-1

Source DB:  PubMed          Journal:  Int J Cardiol        ISSN： 0167-5273            Impact factor:   4.164


  20 in total

1.  Cathepsin-L, a key molecule in the pathogenesis of drug-induced and I-cell disease-mediated gingival overgrowth: a study with cathepsin-L-deficient mice.

Authors:  Fusanori Nishimura; Hisa Naruishi; Koji Naruishi; Teruo Yamada; Junzo Sasaki; Christoph Peters; Yasuo Uchiyama; Yoji Murayama
Journal:  Am J Pathol       Date:  2002-12       Impact factor: 4.307

Review 2.  Nifedipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in ischaemic heart disease, hypertension and related cardiovascular disorders.

Authors:  E M Sorkin; S P Clissold; R N Brogden
Journal:  Drugs       Date:  1985-09       Impact factor: 9.546

3.  Oxodipine-induced gingival hyperplasia in beagle dogs.

Authors:  A Nyska; T Waner; A Zlotogorski; M Pirak; M Scolnik; M Nyska; A Galiano
Journal:  Am J Pathol       Date:  1990-09       Impact factor: 4.307

4.  Gingival hyperplasia with nifedipine.

Authors:  D R Ramsdale; J L Morris; P Hardy
Journal:  Br Heart J       Date:  1995-02

Review 5.  Gingival enlargement induced by drugs.

Authors:  L Brunet; J Miranda; M Farré; L Berini; C Mendieta
Journal:  Drug Saf       Date:  1996-09       Impact factor: 5.606

6.  Prevention of phenytoin-induced gingival overgrowth by lovastatin in mice.

Authors:  Mohammad A Assaggaf; Alpdogan Kantarci; Siddika S Sume; Philip C Trackman
Journal:  Am J Pathol       Date:  2015-04-02       Impact factor: 4.307

Review 7.  Aspects on the benefit-risk balance of felodipine in hypertension.

Authors:  D Elmfeldt; S Westerling
Journal:  Drugs       Date:  1987       Impact factor: 9.546

Review 8.  A comparative review of the adverse effects of calcium antagonists.

Authors:  H T Dougall; J McLay
Journal:  Drug Saf       Date:  1996-08       Impact factor: 5.606

Review 9.  Sustained release nifedipine formulations. An appraisal of their current uses and prospective roles in the treatment of hypertension, ischaemic heart disease and peripheral vascular disorders.

Authors:  D Murdoch; R N Brogden
Journal:  Drugs       Date:  1991-05       Impact factor: 9.546

10.  The effect of angiotensin II on the proliferation of human gingival fibroblasts.

Authors:  Hidenori Oguro; Kohzo Tsuchikawa
Journal:  Odontology       Date:  2009-07-29       Impact factor: 2.634
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