| Literature DB >> 6607354 |
A Terada, S Naruto, K Wachi, S Tanaka, Y Iizuka, E Misaka.
Abstract
[(Cycloalkylmethyl)phenyl]acetic acid derivatives and related compounds were synthesized to test their antiinflammatory and analgesic activities. Some of the compounds in this series were found to have good activity in the carrageenan edema test. Among them, sodium 2-[4-[(2-oxocyclopentyl)methyl] phenyl]propionate dihydrate (15) and 2-[4-[(2-oxocyclohexylidene)methyl]phenyl]propionic acid (13b) showed potent analgesic and antiadjuvant arthritis activities with excellent antipyretic properties.Entities:
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Year: 1984 PMID： 6607354 DOI： 10.1021/jm00368a019
Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 7.446