| Literature DB >> 6607083 |
N Blumberg, D Masel, T Mayer, P Horan, J Heal.
Abstract
Recent evidence suggests that HLA-A,B antigens present on human platelets, are acquired from plasma. Using hypertonic acid chloroquine (200 mg/ml, pH 5.0, 1 hr, 4 degrees C), we demonstrate elution of most or all HLA-A2 and HLA-B7,40 immunoreactive material from platelets. Corresponding antigens on human lymphocytes were not affected by this treatment. These findings are consistent with the hypothesis that HLA-A,B antigens are adsorbed onto platelet surfaces.Entities:
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Year: 1984 PMID： 6607083
Source DB: PubMed Journal: Blood ISSN： 0006-4971 Impact factor: 22.113