Literature DB >> 6606586

Effects of macrolide antibiotics on barbiturate sleeping time in mice.

J Descotes, J C Evreux.   

Abstract

Triacetyloleandomycin and josamycin, when administered to inbred Balb/c mice orally twice daily at a dose of 12.5 or 25 mg per kg over 3 days, were found to increase barbiturate sleeping time significantly. In contrast, erythromycin ethylsuccinate, erythromycin propionate, midecamycin and spiramycin were devoid of any such activity under the same conditions.

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Year:  1983        PMID: 6606586     DOI: 10.1007/bf01990119

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  7 in total

1.  [Pharmacological approach to the mechanism of potentiation of hypnotics by various monoamine oxidase inhibitors].

Authors:  P Simon; J P Tillement; J M Lwoff; J R Boissier
Journal:  Therapie       Date:  1968 Jul-Aug       Impact factor: 2.070

2.  [Delay in elimination of theophylline due to troleandomycin. No effect of josamycin (author's transl)].

Authors:  J L Brazier; J Kofman; G Faucon; M Perrin-Fayolle; A Lepape; R Lanoue
Journal:  Therapie       Date:  1980 Jul-Aug       Impact factor: 2.070

3.  Depression of theophylline metabolism and elimination by troleandomycin and erythromycin.

Authors:  T C Hemsworth; K W Renton
Journal:  Biochem Pharmacol       Date:  1981-06-01       Impact factor: 5.858

4.  Hypoactivity of cytochrome P-450 after triacetyloleandomycin administration.

Authors:  D Pessayre; M Konstantinova-Mitcheva; V Descatoire; B Cobert; J C Wandscheer; R Level; G Feldmann; D Mansuy; J P Benhamou
Journal:  Biochem Pharmacol       Date:  1981-03-15       Impact factor: 5.858

5.  [Influence of josamycine treatment on carbamazepine kinetics (author's transl)].

Authors:  H Albin; G Vinçon; F Pehourcq; J Dangoumau
Journal:  Therapie       Date:  1982 Mar-Apr       Impact factor: 2.070

6.  Lack of effect of intravenous erythromycin lactobionate on theophylline clearance.

Authors:  B J Kimelblatt; R L Slaughter
Journal:  J Allergy Clin Immunol       Date:  1980-04       Impact factor: 10.793

7.  [Influence of a new macrolide, midecamycin on theophylline pharmacokinetics (author's transl)].

Authors:  J Lavarenne; M Paire; O Talon
Journal:  Therapie       Date:  1981 Jul-Aug       Impact factor: 2.070

  7 in total

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