Literature DB >> 6606476

Enteric bacteria and HLA-B27 associated cell surface modification in patients with seronegative spondarthritis.

J Edmonds, A F Geczy, J S Sullivan, J K Prendergast, L I Upfold, H V Bashir.   

Abstract

Cytotoxic studies indicate cross-reactivity between some enteric organisms and cells obtained from the majority of patients with ankylosing spondylitis. Preliminary studies suggest that the factor responsible for cross-reactivity may be generated by a bacterial plasmid. However, the mechanism mediating the interaction between the HLA-B27 positive cell and the bacterial antigen is at present unknown.

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Year:  1983        PMID： 6606476     DOI： 10.1093/rheumatology/xxii.suppl_2.75

Source DB:  PubMed          Journal:  Br J Rheumatol        ISSN： 0263-7103


  7 in total

1.  Polyclonal B cell activation in ankylosing spondylitis.

Authors:  P Barbieri; I Olivieri; G Benedettini; P Marelli; M L Ciompi; G Pasero; M Campa
Journal:  Ann Rheum Dis       Date:  1990-06       Impact factor: 19.103

2.  Klebsiella 'modifying factor': binding studies with HLA-B27+ and B27- lymphocytes.

Authors:  J A Trapani; I F McKenzie
Journal:  Ann Rheum Dis       Date:  1985-03       Impact factor: 19.103

Review 3.  Intestinal permeability, non-steroidal anti-inflammatory drug enteropathy and inflammatory bowel disease: an overview.

Authors:  I Bjarnason; T J Peters
Journal:  Gut       Date:  1989-11       Impact factor: 23.059

4.  HLA-B27 associated cross-reactive marker on the cells of New Zealand patients with ankylosing spondylitis.

Authors:  L E McGuigan; A F Geczy; J K Prendergast; J P Edmonds; H H Hart; H V Bashir
Journal:  Ann Rheum Dis       Date:  1986-02       Impact factor: 19.103

5.  Significance of non-pathogenic cross reactive bowel flora in patients with ankylosing spondylitis.

Authors:  L E McGuigan; J K Prendergast; A F Geczy; J P Edmonds; H V Bashir
Journal:  Ann Rheum Dis       Date:  1986-07       Impact factor: 19.103

6.  The modification of HLA-B27-positive lymphocytes by the culture filtrate of Klebsiella K43 BTS 1 is a metabolically active process.

Authors:  J S Sullivan; A F Geczy
Journal:  Clin Exp Immunol       Date:  1985-12       Impact factor: 4.330

7.  Ankylosing spondylitis, HLA-B27, and Klebsiella: a study of lymphocyte reactivity of anti-Klebsiella sera.

Authors:  B Singh; J D Milton; J C Woodrow
Journal:  Ann Rheum Dis       Date:  1986-03       Impact factor: 19.103
  7 in total

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