Literature DB >> 6606456

Suppression of PHA-induced human T-lymphocyte colony formation following in vivo administration of anti-lymphocyte globulin. Report of one case.

R Ghio, V Pistoia, A Perata, A M Marmont.   

Abstract

The administration of anti-lymphocyte globulin in a patient with pure red cell aplasia completely abrogated the PHA-induced T colony forming capacity of peripheral blood mononuclear cells. The possible mechanisms of the ALG-induced suppression are discussed. It is proposed that T-colony assays may represent an useful tool for monitoring some effects of immunosuppressive drugs on T cells.

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Year:  1983        PMID： 6606456     DOI： 10.1007/bf00320349

Source DB:  PubMed          Journal:  Blut        ISSN： 0006-5242


  11 in total

1.  Clonal proliferation of PHA-stimulated human lymphocytes in soft agar culture.

Authors:  L A Rozenszajn; D Shoham; I Kalechman
Journal:  Immunology       Date:  1975-12       Impact factor: 7.397

2.  Effects of fibroblasts on the growth of erythroid progenitor cells in vitro.

Authors:  R Ghio; G Bianchi; B Löwenberg; K A Dicke; F Ajmar
Journal:  Exp Hematol       Date:  1977-09       Impact factor: 3.084

3.  Erythroid colony formation in cultures of mouse and human bone marrow: analysis of the requirement for erythropoietin by gel filtration and affinity chromatography on agarose-concanavalin A.

Authors:  N N Iscove; F Sieber; K H Winterhalter
Journal:  J Cell Physiol       Date:  1974-04       Impact factor: 6.384

4.  Human bone marrow colony growth in agar-gel.

Authors:  B L Pike; W A Robinson
Journal:  J Cell Physiol       Date:  1970-08       Impact factor: 6.384

5.  Suppressor activity of T cells bearing Fc receptors for IgG on lymphoid colony formation.

Authors:  G W Canonica; V Pistoia; R Ghio; M C Mingari; L Moretta
Journal:  Scand J Immunol       Date:  1980       Impact factor: 3.487

6.  Phytohemagglutinin or pokeweed mitogen induction of in vitro colony formation by T-cells from patients with chronic lymphocytic leukemia.

Authors:  V Pistoia; A Nocera; R Ghio; P Minale; M Ferrarini
Journal:  J Natl Cancer Inst       Date:  1982-02       Impact factor: 13.506

7.  Comparison of the colony-forming capacities of human T-lymphocyte subpopulations.

Authors:  V Pistoia; R Ghio; G W Canonica; M Colombatti; L Moretta
Journal:  Clin Immunol Immunopathol       Date:  1981-12

8.  An assay for serum cytotoxicity against erythroid precursor cells in pure red cell aplasia.

Authors:  B Löwenberg; R Ghio
Journal:  Biomedicine       Date:  1977-11

9.  Human T lymphocyte colonies in agar: a comparison with other T cell assays in healthy subjects and cancer patients.

Authors:  J D Wilson; G Dalton
Journal:  Aust J Exp Biol Med Sci       Date:  1976-02

10.  Pure red cell aplasia (PRCA): Response of three patients of cyclophosphamide and/or antilymphocyte globulin (ALG) and demonstration of two types of serum IgG inhibitors to erythropoiesis.

Authors:  A Marmont; C Peschle; M Sanguineti; M Condorelli
Journal:  Blood       Date:  1975-02       Impact factor: 22.113
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