Literature DB >> 660588

15,15-Ketals of natural prostaglandins and prostaglandin analogues. Synthesis and biological activities.

W Skuballa, B Radüchel, O Loge, W Elger, H Vorbrüggen.   

Abstract

The synthesis is described of new 15,15-ethylene ketals of natural prostaglandins and prostaglandin analogues. Especially the crystalline trisamine salt of the 15,15-ethylene ketal of 15-dehydro-16-phenoxy-17,18,19,20-tetranorprostaglandin F2alpha is a very active inducer of luteolysis in laboratory animals and cattle.

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Year:  1978        PMID: 660588     DOI: 10.1021/jm00203a007

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


  1 in total

1.  Luteolytic potency of 16-phenoxy-derivatives of prostaglandin F2 alpha.

Authors:  N Brambaifa
Journal:  Experientia       Date:  1988-01-15
  1 in total

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