Literature DB >> 6605410

Mouse spleen dendritic cells present soluble antigens to antigen-specific T cell hybridomas.

G H Sunshine, D P Gold, H H Wortis, P Marrack, J W Kappler.   

Abstract

In the presence of the soluble polypeptide antigens ovalbumin and keyhole limpet hemocyanin, purified mouse spleen dendritic cells induce the secretion of IL-2 by antigen-specific T cell hybridomas. This response is H-2 restricted and can be specifically inhibited by monoclonal anti-I-A. These data indicate that dendritic cells can present soluble antigen to H-2-compatible T cells.

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Year:  1983        PMID: 6605410      PMCID: PMC2187132          DOI: 10.1084/jem.158.5.1745

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  17 in total

1.  Long term culture of tumour-specific cytotoxic T cells.

Authors:  S Gillis; K A Smith
Journal:  Nature       Date:  1977-07-14       Impact factor: 49.962

2.  Lymphoid dendritic cells are potent stimulators of the primary mixed leukocyte reaction in mice.

Authors:  R M Steinman; M D Witmer
Journal:  Proc Natl Acad Sci U S A       Date:  1978-10       Impact factor: 11.205

3.  Relative efficacy of human monocytes and dendritic cells as accessory cells for T cell replication.

Authors:  W C Van Voorhis; J Valinsky; E Hoffman; J Luban; L S Hair; R M Steinman
Journal:  J Exp Med       Date:  1983-07-01       Impact factor: 14.307

4.  Rat dendritic cells function as accessory cells and control the production of a soluble factor required for mitogenic responses of T lymphocytes.

Authors:  W E Klinkert; J H LaBadie; J P O'Brien; C F Beyer; W E Bowers
Journal:  Proc Natl Acad Sci U S A       Date:  1980-09       Impact factor: 11.205

5.  Decreased phagocytic and bactericidal activity of the hepatic reticuloendothelial system during chronic ethanol treatment and its restoration by levamisole.

Authors:  D Galante; A Andreana; P Perna; R Utili; G Ruggiero
Journal:  J Reticuloendothel Soc       Date:  1982-09

6.  Antigen-specific, H-2-restricted helper T cell hybridomas.

Authors:  N W Roehm; P Marrack; J W Kappler
Journal:  J Exp Med       Date:  1982-07-01       Impact factor: 14.307

7.  Specialized antigen-presenting cells. Splenic dendritic cells and peritoneal-exudate cells induced by mycobacteria activate effector T cells that are resistant to suppression.

Authors:  J S Britz; P W Askenase; W Ptak; R M Steinman; R K Gershon
Journal:  J Exp Med       Date:  1982-05-01       Impact factor: 14.307

8.  Internalization and degradation of macrophage Fc receptors during receptor-mediated phagocytosis.

Authors:  I S Mellman; H Plutner; R M Steinman; J C Unkeless; Z A Cohn
Journal:  J Cell Biol       Date:  1983-03       Impact factor: 10.539

9.  Dendritic cells are accessory cells for the development of anti-trinitrophenyl cytotoxic T lymphocytes.

Authors:  M C Nussenzweig; R M Steinman; B Gutchinov; Z A Cohn
Journal:  J Exp Med       Date:  1980-10-01       Impact factor: 14.307

10.  Identification of a novel cell type in peripheral lymphoid organs of mice. II. Functional properties in vitro.

Authors:  R M Steinman; Z A Cohn
Journal:  J Exp Med       Date:  1974-02-01       Impact factor: 14.307

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  8 in total

1.  Heterogeneity of accessory cells interacting with T-helper clones.

Authors:  D R Katz; M Feldmann; R Tees; M H Schreier
Journal:  Immunology       Date:  1986-06       Impact factor: 7.397

2.  Functional differences and complementation between dendritic cells and macrophages in T-cell activation.

Authors:  C Guidos; A A Sinha; K C Lee
Journal:  Immunology       Date:  1987-07       Impact factor: 7.397

3.  Monoclonal anti-Ia antibodies suppress the flare up reaction of antigen induced arthritis in mice.

Authors:  M F van den Broek; W B van den Berg; L B van de Putte
Journal:  Clin Exp Immunol       Date:  1986-11       Impact factor: 4.330

Review 4.  Lymphoid dendritic cells.

Authors:  J M Austyn
Journal:  Immunology       Date:  1987-10       Impact factor: 7.397

5.  Human T cell proliferative responses to particulate microbial antigens are supported by populations enriched in dendritic cells.

Authors:  A Mittal; I Nath
Journal:  Clin Exp Immunol       Date:  1987-09       Impact factor: 4.330

6.  Dendritic cells from human tissues express receptors for the immunoregulatory vitamin D3 metabolite, dihydroxycholecalciferol.

Authors:  A Brennan; D R Katz; J D Nunn; S Barker; M Hewison; L J Fraher; J L O'Riordan
Journal:  Immunology       Date:  1987-08       Impact factor: 7.397

7.  Strong priming of T cells adoptively transferred into scid mice.

Authors:  G H Sunshine; B L Jimmo; C Ianelli; L Jarvis
Journal:  J Exp Med       Date:  1991-12-01       Impact factor: 14.307

Review 8.  Toward a Network Model of MHC Class II-Restricted Antigen Processing.

Authors:  Michael A Miller; Asha Purnima V Ganesan; Laurence C Eisenlohr
Journal:  Front Immunol       Date:  2013-12-16       Impact factor: 7.561

  8 in total

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