Literature DB >> 6604786

An HLA-DR5 homozygous cell line expresses two DS (I-A-like) molecules.

R W Karr, C C Kannapell, R J Zangara, S M Goyert, J Silver, B D Schwartz.   

Abstract

Previous studies have indicated that LLA-DR homozygous cell lines express two DR molecules but only a single DS (I-A-like) molecule. This report demonstrates that an HLA-DR5 homozygous cell line expresses at least two distinct DS molecules. These two DS molecules are formed by the association of a single DS alpha chain with either of two DS beta chains. Four distinct Ia molecules have now been identified from this DR5 homozygous cell line.

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Year:  1983        PMID： 6604786      PMCID： PMC2187372          DOI： 10.1084/jem.158.4.1374

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  16 in total

1.  High resolution two-dimensional electrophoresis of proteins.

Authors:  P H O'Farrell
Journal:  J Biol Chem       Date:  1975-05-25       Impact factor: 5.157

2.  A monoclonal antibody detecting an Ia specificity mapping in the I-A or I-E subregion.

Authors:  F W Symington; J Sprent
Journal:  Immunogenetics       Date:  1981       Impact factor: 2.846

3.  Molecular relationships of the human B cell alloantigens, MT2, MB3, MT4, and DR5.

Authors:  R W Karr; C C Kannapell; J A Stein; H M Gebel; D L Mann; R J Duquesnoy; T C Fuller; G E Rodey; B D Schwartz
Journal:  J Immunol       Date:  1982-04       Impact factor: 5.422

4.  Isolation of I-A subregion-like molecules from subhuman primates and man.

Authors:  S M Goyert; J Silver
Journal:  Nature       Date:  1981-11-19       Impact factor: 49.962

5.  Murine Ia and human DR antigens: homology of amino-terminal sequences.

Authors:  J P Allison; L E Walker; W A Russell; M A Pellegrino; S Ferrone; R A Reisfeld; J A Frelinger; J Silver
Journal:  Proc Natl Acad Sci U S A       Date:  1978-08       Impact factor: 11.205

6.  Human B-cell alloantigens DC1, MT1, and LB12 are identical to each other but distinct from the HLA-DR antigen.

Authors:  D A Shackelford; D L Mann; J J van Rood; G B Ferrara; J L Strominger
Journal:  Proc Natl Acad Sci U S A       Date:  1981-07       Impact factor: 11.205

7.  A shared alloantigenic determinant on Ia antigens encoded by the I-A and I-E subregions: evidence for I region gene duplication.

Authors:  A Bhattacharya; M E Dorf; T A Springer
Journal:  J Immunol       Date:  1981-12       Impact factor: 5.422

8.  Structural identity of human histocompatibility leukocyte antigen-B27 molecules from patients with ankylosing spondylitis and normal individuals.

Authors:  R W Karr; Y Hahn; B D Schwartz
Journal:  J Clin Invest       Date:  1982-02       Impact factor: 14.808

9.  Polymorphism and complexity of the human DC and murine I-A alpha chain genes.

Authors:  C Auffray; A Ben-Nun; M Roux-Dosseto; R N Germain; J G Seidman; J L Strominger
Journal:  EMBO J       Date:  1983       Impact factor: 11.598

10.  Biochemical characterization of a second family of human Ia molecules, HLA-DS, equivalent to murine I-A subregion molecules.

Authors:  S M Goyert; J E Shively; J Silver
Journal:  J Exp Med       Date:  1982-08-01       Impact factor: 14.307
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  12 in total

1.  Recognition of class II molecules by human T cells. I. Analysis of epitopes of DR and DQ molecules in a DRw11, DRw52, DQw3 haplotype.

Authors:  L K Myers; E J Ball; G Nuñez; P Stastny
Journal:  Immunogenetics       Date:  1986       Impact factor: 2.846

2.  Interpretation of the specificities of monoclonal antibodies recognising human MHC class II antigens.

Authors:  K Guy; C M Steel
Journal:  Clin Exp Immunol       Date:  1985-01       Impact factor: 4.330

3.  Structure and expression of HLA-DQ alpha and -DX alpha genes: interallelic alternate splicing of the HLA-DQ alpha gene and functional splicing of the HLA-DQ alpha gene using a retroviral vector.

Authors:  C Auffray; J W Lillie; A J Korman; J M Boss; N Fréchin; F Guillemot; J Cooper; R C Mulligan; J L Strominger
Journal:  Immunogenetics       Date:  1987       Impact factor: 2.846

4.  Gene organization of DC and DX subregions of the human major histocompatibility complex.

Authors:  K Okada; J M Boss; H Prentice; T Spies; R Mengler; C Auffray; J Lillie; D Grossberger; J L Strominger
Journal:  Proc Natl Acad Sci U S A       Date:  1985-05       Impact factor: 11.205

5.  Allelic polymorphism and transassociation of molecules encoded by the HLA-DQ subregion.

Authors:  R C Giles; R DeMars; C C Chang; J D Capra
Journal:  Proc Natl Acad Sci U S A       Date:  1985-03       Impact factor: 11.205

6.  Molecular diversity of HLA-DQ. DQ alpha and beta chain isoelectric point differences and their relation to serologically defined HLA-DQ allospecificities.

Authors:  R E Bontrop; E J Baas; N Otting; G M Schreuder; M J Giphart
Journal:  Immunogenetics       Date:  1987       Impact factor: 2.846

7.  Nucleotide sequence of an HLA-DQ alpha chain derived from a DRw9 cell line: genetic and evolutionary implications.

Authors:  J Moriuchi; T Moriuchi; J Silver
Journal:  Proc Natl Acad Sci U S A       Date:  1985-05       Impact factor: 11.205

8.  Polymorphisms of DQ beta genes in HLA-DR4 haplotypes from healthy and diabetic individuals.

Authors:  V Henson; N Maclaren; W Riley; E K Wakeland
Journal:  Immunogenetics       Date:  1987       Impact factor: 2.846

9.  Specificity of the HLA class II reactive monoclonal antibody 33.1.

Authors:  X M Li; J A Sogn; J E Coligan; M C Kuo; G E Marti; L J Edison; T J Kindt
Journal:  Immunogenetics       Date:  1984       Impact factor: 2.846

10.  Identification of two cis-encoded HLA-DQ molecules that carry distinct alloantigenic specificities.

Authors:  J P Johnson; R Wank
Journal:  J Exp Med       Date:  1984-11-01       Impact factor: 14.307
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