| Literature DB >> 6604315 |
H N Wagner, H D Burns, R F Dannals, D F Wong, B Langstrom, T Duelfer, J J Frost, H T Ravert, J M Links, S B Rosenbloom, S E Lukas, A V Kramer, M J Kuhar.
Abstract
Neurotransmitter receptors may be involved in a number of neuropsychiatric disease states. The ligand 3-N-[11C]methylspiperone, which preferentially binds to dopamine receptors in vivo, was used to image the receptors by positron emission tomography scanning in baboons and in humans. This technique holds promise for noninvasive clinical studies of dopamine receptors in humans.Entities:
Mesh：
Substances：
Year: 1983 PMID： 6604315 DOI： 10.1126/science.6604315
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728