Literature DB >> 6603442

Adenovirus fiber protein produces synthesis of interferon in mouse spleen and macrophage cultures.

P Tiensiwakul, N Khoobyarian.   

Abstract

An inhibitor of viral activity appears in BALB/c mice spleen cells and macrophage cultures treated with adenovirus 2 fiber protein. This inhibitor was partially characterized and identified as type I interferon. Macrophage cultures produced higher titers of this interferon than did spleen cells. Thus, a purified viral protein with B-cell mitogenic activity induced synthesis of interferon in murine cells.

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Year:  1983        PMID： 6603442     DOI： 10.1159/000149374

Source DB:  PubMed          Journal:  Intervirology        ISSN： 0300-5526            Impact factor:   1.763


  3 in total

1.  Induction of alpha interferon by transmissible gastroenteritis coronavirus: role of transmembrane glycoprotein E1.

Authors:  B Charley; H Laude
Journal:  J Virol       Date:  1988-01       Impact factor: 5.103

2.  Mouse adenovirus type 1 infection in SCID mice: an experimental model for antiviral therapy of systemic adenovirus infections.

Authors:  L Lenaerts; E Verbeken; E De Clercq; L Naesens
Journal:  Antimicrob Agents Chemother       Date:  2005-11       Impact factor: 5.191

3.  Adenovirus hexon protein is a potent adjuvant for activation of a cellular immune response.

Authors:  Valérie Molinier-Frenkel; Renée Lengagne; Florence Gaden; Saw-See Hong; Jeannine Choppin; Hanne Gahery-Ségard; Pierre Boulanger; Jean-Gérard Guillet
Journal:  J Virol       Date:  2002-01       Impact factor: 5.103
  3 in total

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