Literature DB >> 6602381

Antipyretic potency of centrally administered alpha-melanocyte stimulating hormone.

M T Murphy, D B Richards, J M Lipton.   

Abstract

Centrally administered alpha-melanocyte stimulating hormone is much more potent in reducing fever than the widely used antipyretic acetaminophen. This finding supports the hypothesis that the endogenous neuropeptide has a role in the limitation of fever and suggests that it may be clinically useful as an antipyretic.

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Year:  1983        PMID： 6602381     DOI： 10.1126/science.6602381

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  16 in total

1.  Effects of alpha-melanocyte stimulating hormone on fever caused by endotoxin in rabbits.

Authors:  K Goelst; D Mitchell; H Laburn
Journal:  J Physiol       Date:  1991-09       Impact factor: 5.182

2.  Intracerebroventricular infusion of interleukin 1 rapidly decreases peripheral cellular immune responses.

Authors:  S K Sundar; K J Becker; M A Cierpial; M D Carpenter; L A Rankin; S L Fleener; J C Ritchie; P E Simson; J M Weiss
Journal:  Proc Natl Acad Sci U S A       Date:  1989-08       Impact factor: 11.205

3.  Human immunodeficiency virus glycoprotein (gp120) infused into rat brain induces interleukin 1 to elevate pituitary-adrenal activity and decrease peripheral cellular immune responses.

Authors:  S K Sundar; M A Cierpial; L S Kamaraju; S Long; S Hsieh; C Lorenz; M Aaron; J C Ritchie; J M Weiss
Journal:  Proc Natl Acad Sci U S A       Date:  1991-12-15       Impact factor: 11.205

4.  Profound and rapid reduction in body temperature induced by the melanocortin receptor agonists.

Authors:  Yuanzhong Xu; Eun Ran Kim; Shengjie Fan; Yan Xia; Yong Xu; Cheng Huang; Qingchun Tong
Journal:  Biochem Biophys Res Commun       Date:  2014-07-24       Impact factor: 3.575

5.  Biphasic effect of melanocortin agonists on metabolic rate and body temperature.

Authors:  Beth Lute; William Jou; Dalya M Lateef; Margalit Goldgof; Cuiying Xiao; Ramón A Piñol; Alexxai V Kravitz; Nicole R Miller; Yuning George Huang; Clemence Girardet; Andrew A Butler; Oksana Gavrilova; Marc L Reitman
Journal:  Cell Metab       Date:  2014-06-26       Impact factor: 27.287

6.  Melanotan II causes hypothermia in mice by activation of mast cells and stimulation of histamine 1 receptors.

Authors:  Shalini Jain; Anna Panyutin; Naili Liu; Cuiying Xiao; Ramón A Piñol; Priyanka Pundir; Clémence Girardet; Andrew A Butler; Xinzhong Dong; Oksana Gavrilova; Marc L Reitman
Journal:  Am J Physiol Endocrinol Metab       Date:  2018-05-29       Impact factor: 4.310

7.  Cloning, expression, and tissue distribution of a fifth melanocortin receptor subtype.

Authors:  Z Fathi; L G Iben; E M Parker
Journal:  Neurochem Res       Date:  1995-01       Impact factor: 3.996

8.  Neuropeptide regulation of interleukin-1 activities. Capacity of alpha-melanocyte stimulating hormone to inhibit interleukin-1-inducible responses in vivo and in vitro exhibits target cell selectivity.

Authors:  B A Robertson; L C Gahring; R A Daynes
Journal:  Inflammation       Date:  1986-12       Impact factor: 4.092

9.  Combinatorial diffusion assay used to identify topically active melanocyte-stimulating hormone receptor antagonists.

Authors:  J M Quillan; C K Jayawickreme; M R Lerner
Journal:  Proc Natl Acad Sci U S A       Date:  1995-03-28       Impact factor: 11.205

10.  Analysis of the antipyretic action of alpha-melanocyte-stimulating hormone in rabbits.

Authors:  W G Clark; M Holdeman; J M Lipton
Journal:  J Physiol       Date:  1985-02       Impact factor: 5.182
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