| Literature DB >> 6602378 |
S R Bergmann, K A Fox, M M Ter-Pogossian, B E Sobel, D Collen.
Abstract
Coronary thrombolysis, an intervention that can abort the sequelae of acute myocardial infarction, was accomplished within 10 minutes in dogs by intravenous administration of clot-selective, tissue-type plasminogen activator. In addition to inducing clot lysis, this promising fibrinolytic agent restored intermediary metabolism and nutritional myocardial blood flow, detectable noninvasively with positron tomography, without inducing a systemic fibrinolytic state.Entities:
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Year: 1983 PMID: 6602378 DOI: 10.1126/science.6602378
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728