Literature DB >> 6602365

The nature of hairy cells - a study with a panel of monoclonal antibodies.

C P Worman, D A Brooks, N Hogg, H Zola, P C Beverley, J C Cawley.   

Abstract

In all 11 patients with hairy-cell leukaemia (HCL) tested, a high percentage of peripheral blood and splenic (3 cases) hairy cells (HCs) reacted with 2 B-cell-specific monoclonal antibodies (FMC1 and FMC7), but failed to stain with 5 monocyte/macrophage-specific (FMC17, UCHM1, SM1, SMø and OKM1) and with 4 T-cell-specific antibodies (UCHT1, Leu1, 2a and 3a). The data provide further evidence in support of the B-cell nature of the HCs of HCL.

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Year:  1983        PMID: 6602365     DOI: 10.1111/j.1600-0609.1983.tb01479.x

Source DB:  PubMed          Journal:  Scand J Haematol        ISSN: 0036-553X


  4 in total

1.  Hairy cell leukemia: 1986.

Authors:  D Catovsky
Journal:  Br Med J (Clin Res Ed)       Date:  1986-03-22

2.  Alpha-interferon induces remission in hairy cell leukemia without enhancement of natural killing.

Authors:  G Gastl; W Aulitzky; E Leiter; R Flener; C Huber
Journal:  Blut       Date:  1986-05

3.  Further evidence for the B-cell nature of hairy cells. A study using immunostaining of splenic tissue with a wide panel of monoclonal antibodies.

Authors:  G Pallesen; G Kerndrup; J Ellegaard
Journal:  Blut       Date:  1984-11

4.  Membrane phenotypic studies in B cell lymphoproliferative disorders.

Authors:  C S Scott; H J Limbert; I D MacKarill; B E Roberts
Journal:  J Clin Pathol       Date:  1985-09       Impact factor: 3.411

  4 in total

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