Literature DB >> 6599404

Interpretation of LOD scores with a set of marker loci.

E A Thompson.   

Abstract

The problem discussed is that of interpreting LOD scores when multiple markers are tested for linkage with a particular disease locus. Provided the tests are based on independent segregations, both the maximum and the average LOD can be translated into a score that would have the same significance level were it the result of a single test.

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Year:  1984        PMID： 6599404     DOI： 10.1002/gepi.1370010407

Source DB:  PubMed          Journal:  Genet Epidemiol        ISSN： 0741-0395            Impact factor:   2.135


  6 in total

1.  A confidence-set approach for finding tightly linked genomic regions.

Authors:  S Lin; J A Rogers; J C Hsu
Journal:  Am J Hum Genet       Date:  2001-04-13       Impact factor: 11.025

2.  A note on multiple testing procedures in linkage analysis.

Authors:  N Risch
Journal:  Am J Hum Genet       Date:  1991-06       Impact factor: 11.025

3.  Status of the search for a major genetic locus for affective disorder in the Old Order Amish.

Authors:  A J Pakstis; J R Kidd; C M Castiglione; K K Kidd
Journal:  Hum Genet       Date:  1991-08       Impact factor: 4.132

4.  Reply to "The question of heterogeneity in Marfan syndrome"

Authors:  Catherine Boileau; Claudine Junien; Gwenaëlle Collod; Guillaume Jondeau; Olivier Dubourg; Jean-Pierre Bourdarias; Catherine Bonaïti-Pellié; Jean Frezal; Pierre Maroteaux
Journal:  Nat Genet       Date:  1995-03       Impact factor: 38.330

5.  Multipoint linkage analysis.

Authors:  N E Morton; C J MacLean; R Lew; S Yee
Journal:  Am J Hum Genet       Date:  1986-06       Impact factor: 11.025

6.  Exclusion mapping.

Authors:  J H Edwards
Journal:  J Med Genet       Date:  1987-09       Impact factor: 6.318
  6 in total

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