Literature DB >> 659870

The requirement for the Fc portion of antibody in antigen-antibody complex-mediated suppression.

E L Morgan, C H Tempelis.   

Abstract

The role of the Fc portion of antibody in immune complex-induced suppression was studied in vivo and in vitro. BSA pheasant anti-BSA complexes, formed in antigen excess (Ag1Ab1), were found to suppress both responses to BSA and SRBC. When complexes were formed with F(ab')2 fragments of pheasant anti-BSA, no suppression was observed, indicating that the Fc piece was indeed essential for the induction of Ag-Ab complex-mediated suppression.

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Year:  1978        PMID： 659870

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  12 in total

1.  Functional capacity of immunoglobulin G preparations and the F(ab')2 split product.

Authors:  R W Steele; R W Steele
Journal:  J Clin Microbiol       Date:  1989-04       Impact factor: 5.948

2.  The biological properties of immunoglobulin G and its split products [F(ab')2 and Fab].

Authors:  H H Sedlacek; P Gronski; T Hofstaetter; E J Kanzy; H U Schorlemmer; F R Seiler
Journal:  Klin Wochenschr       Date:  1983-08-01

3.  Suppressive B-cell factor (SBF) produced by FcR-bearing B cells; suppression of B, but not non-B-cell proliferation.

Authors:  T Suzuki; M Miyama-Inaba; T Masuda; H Uchino; A Murakami; H Tanaka
Journal:  Immunology       Date:  1983-09       Impact factor: 7.397

4.  Generation of suppressor cells by aggregated human globulin.

Authors:  J P Antel; M E Medof; J J Oger; H H Kuo; B G Arnason
Journal:  Clin Exp Immunol       Date:  1981-02       Impact factor: 4.330

5.  Recombinant IgG2a Fc (M045) multimers effectively suppress experimental autoimmune myasthenia gravis.

Authors:  Muthusamy Thiruppathi; Jian Rong Sheng; Liangcheng Li; Bellur S Prabhakar; Matthew N Meriggioli
Journal:  J Autoimmun       Date:  2014-01-02       Impact factor: 7.094

6.  Immunosuppression of anti-sheep erythrocyte responses by glycerol teichoic acid immune complexes.

Authors:  R W Bolton
Journal:  Infect Immun       Date:  1980-12       Impact factor: 3.441

7.  Monoclonal SBF produced by a hybridoma: in-vitro and in-vivo suppression of B tumour-cell proliferation.

Authors:  T Suzuki; M Miyama-Inaba; T Masuda; H Uchino; K Ishii
Journal:  Immunology       Date:  1983-12       Impact factor: 7.397

8.  Pathopysiological aspects of immune complex diseases. Part II. Phagocytosis, exocytosis, and pathogenic depositions.

Authors:  H H Sedlacek
Journal:  Klin Wochenschr       Date:  1980-06-16

9.  Fully recombinant IgG2a Fc multimers (stradomers) effectively treat collagen-induced arthritis and prevent idiopathic thrombocytopenic purpura in mice.

Authors:  Ajay Jain; Henrik S Olsen; Ravi Vyzasatya; Erin Burch; Yukimi Sakoda; Emmanuel Y Mérigeon; Ling Cai; Changwan Lu; Ming Tan; Koji Tamada; Dan Schulze; David S Block; Scott E Strome
Journal:  Arthritis Res Ther       Date:  2012-08-20       Impact factor: 5.156

10.  Selective proteolysis of immunoglobulins by mouse macrophage elastase.

Authors:  M J Banda; E J Clark; Z Werb
Journal:  J Exp Med       Date:  1983-04-01       Impact factor: 14.307
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