| Literature DB >> 6597939 |
E A Stone, R Trullas, J E Platt.
Abstract
Rats were given single or repeated injection of desmethylimipramine (DMI) and subjected to a single session of restraint or footshock stress. The degree of anorexia and plasma corticosterone elevation in response to the stress was measured. Repeated but not single injection of DMI was found to reduce the anorectic response to restraint and footshock but not to affect the corticosterone response to restraint. It is concluded that repeated DMI treatment has differential effects on responses to acute stress.Entities:
Mesh：
Substances：
Year: 1984 PMID： 6597939 DOI： 10.1016/0278-5846(84)90019-8
Source DB: PubMed Journal: Prog Neuropsychopharmacol Biol Psychiatry ISSN： 0278-5846 Impact factor: 5.067