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Literature DB >> 6595498

Erythroleukemia (K562) cells contain a functional beta-globin gene.

M Donovan-Peluso, K Young, C Dobkin, A Bank.

Abstract

K562 cells are human erythroid cells that synthesize embryonic and fetal globins but not adult beta-globin. A cloned beta-globin gene was isolated from K562 cells and transfected into HeLa cells. The RNA transcripts produced were comparable in both amount and size to those obtained with a normal beta-globin gene.

Entities: Disease Species

Mesh：

Substances：
Globins

Year: 1984 PMID： 6595498 PMCID： PMC369090 DOI： 10.1128/mcb.4.11.2553-2555.1984

Source DB: PubMed Journal: Mol Cell Biol ISSN： 0270-7306 Impact factor: 4.272

17 in total

1. Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids.

Authors: A J Berk; P A Sharp
Journal: Cell Date: 1977-11 Impact factor: 41.582

2. K562 human leukaemic cells synthesise embryonic haemoglobin in response to haemin.

Authors: T R Rutherford; J B Clegg; D J Weatherall
Journal: Nature Date: 1979-07-12 Impact factor: 49.962

3. Screening lambdagt recombinant clones by hybridization to single plaques in situ.

Authors: W D Benton; R W Davis
Journal: Science Date: 1977-04-08 Impact factor: 47.728

4. Mapping of RNA by a modification of the Berk-Sharp procedure: the 5' termini of 15 S beta-globin mRNA precursor and mature 10 s beta-globin mRNA have identical map coordinates.

Authors: R F Weaver; C Weissmann
Journal: Nucleic Acids Res Date: 1979-11-10 Impact factor: 16.971

5. Ribonucleic acid isolated by cesium chloride centrifugation.

Authors: V Glisin; R Crkvenjakov; C Byus
Journal: Biochemistry Date: 1974-06-04 Impact factor: 3.162

6. The isolation of structural genes from libraries of eucaryotic DNA.

Authors: T Maniatis; R C Hardison; E Lacy; J Lauer; C O'Connell; D Quon; G K Sim; A Efstratiadis
Journal: Cell Date: 1978-10 Impact factor: 41.582

7. DNA methylation in the human gamma delta beta-globin locus in erythroid and nonerythroid tissues.

Authors: L H van der Ploeg; R A Flavell
Journal: Cell Date: 1980-04 Impact factor: 41.582

8. Electrophoretic separation of human embryonic globin demonstrates "alpha-thalassemia" in human leukemia cell line K562.

Authors: B P Alter; S C Goff
Journal: Biochem Biophys Res Commun Date: 1980-06-16 Impact factor: 3.575

9. Embryonic-fetal erythroid characteristics of a human leukemic cell line.

Authors: E J Benz; M J Murnane; B L Tonkonow; B W Berman; E M Mazur; C Cavallesco; T Jenko; E L Snyder; B G Forget; R Hoffman
Journal: Proc Natl Acad Sci U S A Date: 1980-06 Impact factor: 11.205

10. Specific globin mRNAs in human erythroleukemia (K562) cells.

Authors: C W Miller; K Young; D Dumenil; B P Alter; J M Schofield; A Bank
Journal: Blood Date: 1984-01 Impact factor: 22.113

4 in total

1. Trans acting regulation of beta globin gene expression in erythroleukemia (K562) cells.

Authors: K Young; M Donovan-Peluso; R Cubbon; A Bank
Journal: Nucleic Acids Res Date: 1985-07-25 Impact factor: 16.971

2. Differential expression of alpha- and beta-globin genes in erythroleukemic cell lines.

Authors: N Beru; P B Maples; O Hermine; E Goldwasser
Journal: Mol Cell Biol Date: 1990-07 Impact factor: 4.272

3. Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids.

Authors: W C Forrester; S Takegawa; T Papayannopoulou; G Stamatoyannopoulos; M Groudine
Journal: Nucleic Acids Res Date: 1987-12-23 Impact factor: 16.971

4. Activation of the human beta-globin promoter in K562 cells by DNA sequences 5' to the fetal gamma- or embryonic zeta-globin genes.

Authors: H J Lin; N P Anagnou; T R Rutherford; T Shimada; A W Nienhuis
Journal: J Clin Invest Date: 1987-08 Impact factor: 14.808

4 in total