Literature DB >> 6595116

Immunoscintigraphy and distribution study of experimental tumours using 131I-labelled anti-fibrinogen antibodies.

P Svihovcová, H Koprivová, A Glagolicová, F Novák, H Sůrová, Z Dienstbier.   

Abstract

131I-labelled antibodies to the fragment E of human fibrin, anti-rat fibrinogen, non-immune rabbit IgG and 67Ga-citrate were used for scintigraphy and distribution studies in experimental tumours in rats. The best visualisation was achieved with 131I-labelled anti-rat fibrinogen antibodies at intervals longer than 48 h after administration. Tumour to tissue ratios found in distribution studies performed formed more than 48 h after administration were higher in most examined tissues when using 131I-labelled antibodies than those obtained with 67Ga-citrate.

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Year:  1984        PMID： 6595116     DOI： 10.1007/bf00563173

Source DB:  PubMed          Journal:  Eur J Nucl Med        ISSN： 0340-6997


  17 in total

1.  EFFICIENT LABELLING OF SERUM PROTEINS WITH I-131 USING CHLORAMINE T.

Authors:  V BOCCI
Journal:  Int J Appl Radiat Isot       Date:  1964-08

2.  Localization of antifibrin antibodies in human tumors.

Authors:  W C DEWEY; W F BALE; R G ROSE; D MARRACK
Journal:  Acta Unio Int Contra Cancrum       Date:  1963

3.  Coagulative properties of cancers.

Authors:  R A O'MEARA
Journal:  Ir J Med Sci       Date:  1958-10       Impact factor: 1.568

4.  Localization in vivo of radio-iodinated anti-rat-fibrin antibodies and radio-iodinated rat fibrinogen in the Murphy rat lymphosarcoma and in other transplantable rat tumors.

Authors:  E D DAY; J A PLANINSEK; D PRESSMAN
Journal:  J Natl Cancer Inst       Date:  1959-02       Impact factor: 13.506

5.  Fibrin in human tumors.

Authors:  R HIRAMOTO; J BERNECKY; J JURANDOWSKI; D PRESSMAN
Journal:  Cancer Res       Date:  1960-06       Impact factor: 12.701

6.  The zone of activity of antibodies as determined by the use of radioactive tracers; the zone of activity of nephritoxic antikidney serum.

Authors:  D PRESSMAN; G KEIGHLEY
Journal:  J Immunol       Date:  1948-06       Impact factor: 5.422

7.  Localization of intracranial tumors. Comparative study with 131-I-labeled antibody to human fibrinogen and neohydrin-203Hg.

Authors:  D Marrack; M Kubala; P Corry; M Leavens; J Howze; W Dewey; W F Bale; I L Spar
Journal:  Cancer       Date:  1967-05       Impact factor: 6.860

8.  Studies with iodine-131-labeled antibody to human fibrinogen for diagnosis and therapy of tumors.

Authors:  R J McCardle; P V Harper; I L Spar; W F Bale; G Andros; F Jiminez
Journal:  J Nucl Med       Date:  1966-11       Impact factor: 10.057

9.  Use of limitations of radiolabeled anti-CEA antibodies and their fragments for photoscanning detection of human colorectal carcinomas.

Authors:  J P Mach; M Forni; J Ritschard; F Buchegger; S Carrel; S Widgren; A Donath; P Alberto
Journal:  Oncodev Biol Med       Date:  1980-08

10.  Factors influencing localization of labeled antibodies in tumors.

Authors:  W F Bale; M A Contreras; E D Grady
Journal:  Cancer Res       Date:  1980-08       Impact factor: 12.701
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