Literature DB >> 6594712

Plasma and red cell levels of thioridazine and clinical response in schizophrenia.

R C Smith, R Baumgartner, G K Ravichandran, A Shvartsburd, J C Schoolar, P Allen, R Johnson.   

Abstract

The relationship of plasma and red blood cell (RBC) levels of thioridazine to clinical response in schizophrenia was evaluated in a fixed-dose study. Steady-state plasma and RBC levels of thioridazine, mesoridazine, and sum of thioridazine and mesoridazine, determined by gas-liquid chromatography, were not significantly correlated with clinical response as measured by improvement on the Brief Psychiatric Rating Scale. RBC thioridazine levels were not substantially more strongly correlated with clinical response than plasma levels.

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Year:  1984        PMID: 6594712     DOI: 10.1016/0165-1781(84)90045-3

Source DB:  PubMed          Journal:  Psychiatry Res        ISSN: 0165-1781            Impact factor:   3.222


  5 in total

1.  Unbound plasma concentrations, total plasma concentrations, and red blood cell concentrations of thioridazine and its main metabolites: an in vitro study.

Authors:  G Nyberg; E Mårtensson
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1987-04       Impact factor: 3.000

Review 2.  Cancer and the Dopamine D2 Receptor: A Pharmacological Perspective.

Authors:  Jillian S Weissenrieder; Jeffrey D Neighbors; Richard B Mailman; Raymond J Hohl
Journal:  J Pharmacol Exp Ther       Date:  2019-04-18       Impact factor: 4.030

Review 3.  Plasma level monitoring of antipsychotic drugs. Clinical utility.

Authors:  S G Dahl
Journal:  Clin Pharmacokinet       Date:  1986 Jan-Feb       Impact factor: 6.447

4.  Comparative efficacy of red cell and plasma haloperidol as predictors of clinical response in schizophrenia.

Authors:  R C Smith; R Baumgartner; A Shvartsburd; G K Ravichandran; G Vroulis; M Mauldin
Journal:  Psychopharmacology (Berl)       Date:  1985       Impact factor: 4.530

5.  GEPSI: A Gene Expression Profile Similarity-Based Identification Method of Bioactive Components in Traditional Chinese Medicine Formula.

Authors:  Baixia Zhang; Shuaibing He; Chenyang Lv; Yanling Zhang; Yun Wang
Journal:  Evid Based Complement Alternat Med       Date:  2018-03-06       Impact factor: 2.629

  5 in total

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