Literature DB >> 6593748

The effect of prostaglandin D2 (PGD2) on circulating eosinophils.

K A Marsden, P S Rao, D Cavanagh, E Spaziani.   

Abstract

Infusion of prostaglandin D2 (PGD2) into dogs for 60 minutes at a rate of 1 microgram/kg/min produced a marked and rapid reduction in circulating eosinophils within 2 minutes, without any significant change in neutrophil count. Recovery was also rapid, with levels similar to those of a control group of dogs being reached 60 minutes after finishing the infusion. In dogs given PGD2 the hematocrit rose more rapidly than in the control group. The platelet count did not alter significantly.

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Year:  1984        PMID: 6593748     DOI: 10.1016/0262-1746(84)90137-9

Source DB:  PubMed          Journal:  Prostaglandins Leukot Med        ISSN: 0262-1746


  2 in total

1.  In vivo induction of neutrophilia, lymphopenia, and diminution of neutrophil adhesion by stable analogs of prostaglandins E1, E2, and F2 alpha.

Authors:  T R Ulich; E B Dakay; J H Williams; R X Ni
Journal:  Am J Pathol       Date:  1986-07       Impact factor: 4.307

Review 2.  The therapeutic potential of CRTH2/DP2 beyond allergy and asthma.

Authors:  Katharina Jandl; Akos Heinemann
Journal:  Prostaglandins Other Lipid Mediat       Date:  2017-08-14       Impact factor: 3.072

  2 in total

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