| Literature DB >> 6592118 |
A Mustonen, J Ilonen, H M Surcel, H K Akerblom.
Abstract
The HLA antigen combination A9, Bw16 has been found to be associated with Type 1 (insulin-dependent) diabetes characterized by some special features in Northern Finland. This antigen combination has now been associated with a 'new' DR4-associated D antigen, provisionally called 'JA' or 'SN'. This 'new' D specificity was also associated with HLA-B18. Although the combination, Dw3/DJA, was common in Type 1 diabetic patients, the frequency of the combination Dw4/DJA was decreased compared with the expected value. This supports the hypothesis of two different risk factors associated with DR3 and DR4.Entities:
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Year: 1984 PMID: 6592118 DOI: 10.1007/bf00275668
Source DB: PubMed Journal: Diabetologia ISSN: 0012-186X Impact factor: 10.122