Literature DB >> 6591909

Extradural chloroma with spinal compression--an unusual presentation of acute myelogenous leukemia.

S J Kellie, K D Waters.   

Abstract

Chloromas are solid tumours resulting from the localised proliferation of myelogenous leukemia cells, and are frequently responsible for the initial manifestations of acute myelocytic leukemia. We report a patient with a thoracic extradural chloroma whose presentation with acute paraplegia led to the diagnosis of an unsuspected myelocytic leukemia. Early recognition of the etiology of the paraplegia and the underlying systemic involvement with leukemia resulted in an excellent neurological and hematological outcome. The previously described association of the 8:21 chromosomal translocation with a good prognosis is noted in our patient.

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Year:  1984        PMID: 6591909     DOI: 10.1111/j.1445-5994.1984.tb04281.x

Source DB:  PubMed          Journal:  Aust N Z J Med        ISSN: 0004-8291


  5 in total

1.  Acute quadriplegia as a presenting symptom of acute myeloid leukemia.

Authors:  R Sharma; N Mangal; U Acherya; K Devpura
Journal:  Indian J Pediatr       Date:  1995 Nov-Dec       Impact factor: 1.967

2.  Granulocytic sarcoma (chloroma) causing spinal cord compression.

Authors:  B J Frohna; D J Quint
Journal:  Neuroradiology       Date:  1993       Impact factor: 2.804

3.  Therapeutic modalities for central nervous system involvement by granulocytic sarcoma (chloroma) in children with acute nonlymphocytic leukemia.

Authors:  Y Takaue; S J Culbert; T Baram; A Cork; J M Trujillo
Journal:  J Neurooncol       Date:  1987       Impact factor: 4.130

4.  Paraparesis secondary to a spinal mass as the presenting feature of erythroleukaemia in a 10-month-old child.

Authors:  I Slavc; C Urban; J Ritter; P F Ambros; O A Haas; U Köller; R Kurz
Journal:  Eur J Pediatr       Date:  1992-05       Impact factor: 3.183

5.  Acute myeloid leucaemia presenting as a rapidly progressive polyradiculoneuropathy.

Authors:  Claire L Hirst; Mark Willis; Hussain Hussain; Rob Powell
Journal:  BMJ Case Rep       Date:  2015-11-18
  5 in total

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