Acute posterior multifocal placoid pigment epitheliopathy. A follow up study.

Thirteen patients with acute posterior multifocal placoid pigment epitheliopathy (APMPPE) were followed up for a period of from 1 to 20 years (median 5 years 8 months). Five patients developed lesions in the previously unaffected fellow eye during the follow up period. In three patients the condition progressed during a prolonged period without interruption. Widespread severe choroidal atrophy was a late feature in a number of cases. In seven out of thirteen cases, visual acuity remained defective (6/18 or less) in one or both eyes. The prevailing opinion that that APMPPE is self limiting may be incorrect.