Literature DB >> 659022

Site of respiratory reaction in allergic rats challenged via the airways.

F Carswell, J Oliver.   

Abstract

Rats systemically sensitized to DNP-ovalbumin show a characteristic respiratory response to antigen challenge delivered via the airway. The slowing of expiratory air flow which occurs on aerosol challenge still occurs when the antigen is injected via a tracheostomy but not when it is delivered solely to the upper airways. Disodium cromoglycate administered via the tracheostomy 1 min before intratracheal antigen challenge reduces the respiratory response.

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Year:  1978        PMID： 659022     DOI： 10.1159/000232125

Source DB:  PubMed          Journal:  Int Arch Allergy Appl Immunol        ISSN： 0020-5915


  5 in total

1.  Reduced tracheal mast cell numbers in adjuvant-sensitized rats associated with reduced pulmonary reactivity.

Authors:  F Carswell; J Oliver
Journal:  Immunology       Date:  1980-07       Impact factor: 7.397

2.  Lanthanum penetration of the trachea after the immediate response of sensitized rats to aerosol antigen.

Authors:  S Mukherjee; P Heap; F Carswell
Journal:  Clin Exp Immunol       Date:  1986-09       Impact factor: 4.330

3.  Effect of aerosol challenge with sensitising antigen on the permeability of the surface of the rat trachea in life.

Authors:  S Mukherjee; P Heap; F Carswell
Journal:  Thorax       Date:  1988-12       Impact factor: 9.139

4.  The derivation of an inbred line of rats which develop asthma-like symptoms following challenge with aerosolized antigen.

Authors:  G Holme; H Piechuta
Journal:  Immunology       Date:  1981-01       Impact factor: 7.397

5.  The respiratory response of sensitized rats to challenge with antigen aerosols.

Authors:  H Piechuta; M E Smith; N N Share; G Holme
Journal:  Immunology       Date:  1979-10       Impact factor: 7.397
  5 in total

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