| Literature DB >> 6589791 |
N K Honey, A Y Sakaguchi, P A Lalley, C Quinto, R J MacDonald, C Craik, G I Bell, W J Rutter, S L Naylor.
Abstract
The mouse genes for the serine proteases trypsin (Try-1), chymotrypsin B (Ctrb), and elastase (Ela-1) were chromosomally assigned using Southern blot hybridization of mouse X Chinese hamster cell hybrid DNA. cDNA probes for the three genes were hybridized to cell hybrid DNA cleaved with BamHI or HindIII and the segregation of Try-1, Ctrb, and Ela-1 was correlated with the segregation of mouse chromosomes. Try-1 is located on chromosome 6, Ctrb is on chromosome 8, and Ela-1 is on chromosome 15. The three genes fall into three syntenic groups that are conserved in the mouse and human genomes.Entities:
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Year: 1984 PMID: 6589791 DOI: 10.1007/bf01535633
Source DB: PubMed Journal: Somat Cell Mol Genet ISSN: 0740-7750