Cranial base dynamics in craniofacial dysostosis.

Cephalometric analyses of twenty-one patients with Crouzon's disease were undertaken to correlate the cranial base abnormalities to altered facial morphology. Angular deformities of the cranial base, i.e., the vertical sloping of the anterior cranial fossa and the angulation of the cranial base flexure were found to correlate well to observed exorbitism and midface retrusion , respectively. Normal craniofacial growth and clinical implications of these data are discussed.