Literature DB >> 6584514

Decreased fibronectin biosynthesis by human cord blood mononuclear phagocytes in vitro.

J S Gerdes, S D Douglas, G B Kolski, M C Yoder, R A Polin.   

Abstract

Cultured cord blood monocytes synthesize significantly less fibronectin than cultured monocyte-macrophages from adult peripheral blood. Biosynthesis of the second component of complement in vitro is similar for both cell systems. The monocyte-macrophages from neonates and adults have similar functional and morphologic properties in long-term cultures. The decreased monocyte-macrophage biosynthesis of fibronectin observed in vitro may be in part related to the reduced plasma fibronectin concentrations and reticuloendothelial system hypofunction which occur in newborn infants.

Entities:  

Mesh：

Substances：

Year:  1984        PMID： 6584514     DOI： 10.1002/jlb.35.1.91

Source DB:  PubMed          Journal:  J Leukoc Biol        ISSN： 0741-5400            Impact factor:   4.962


  5 in total

1.  Plasma fibronectin concentrations in healthy newborns and in children.

Authors:  E A Valletta; L Bonazzi; R Zuanazzi; G Del Col; A Andreoli; L Stocchero; A L Boner
Journal:  Eur J Pediatr       Date:  1988-01       Impact factor: 3.183

2.  Evaluation of fibronectin gene expression by in situ hybridization. Differential expression of the fibronectin gene among populations of human alveolar macrophages.

Authors:  K Adachi; K Yamauchi; J F Bernaudin; P Fouret; V J Ferrans; R G Crystal
Journal:  Am J Pathol       Date:  1988-11       Impact factor: 4.307

3.  The accumulation of inflammatory cells in synovial sheath and epitenon during adhesion formation in healing rat flexor tendons.

Authors:  B Wojciak; J F Crossan
Journal:  Clin Exp Immunol       Date:  1993-07       Impact factor: 4.330

4.  Modulation of fibronectin gene expression in human mononuclear phagocytes.

Authors:  K Yamauchi; Y Martinet; R G Crystal
Journal:  J Clin Invest       Date:  1987-12       Impact factor: 14.808

5.  Connective tissue proteins and phagocytic cell function. Laminin enhances complement and Fc-mediated phagocytosis by cultured human macrophages.

Authors:  J F Bohnsack; H K Kleinman; T Takahashi; J J O'Shea; E J Brown
Journal:  J Exp Med       Date:  1985-05-01       Impact factor: 14.307
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.