Literature DB >> 6584256

Thymic hormone containing cells. IV. Fluctuations in the thyroid hormone levels in vivo can modulate the secretion of thymulin by the epithelial cells of young mouse thymus.

W Savino, B Wolf, S Aratan-Spire, M Dardenne.   

Abstract

The influence of thyroid status on serum level and thymic content of thymulin, a thymic hormone, has been studied in young rats and mice treated by tri-iodothyronine (T3) or 6N-propyl-2-thiouracil (PTU). We showed that in vivo T3 administration induces in young animals an increase of their thymulin serum levels and of the number of thymulin containing cells in their thymuses. Conversely, a treatment with PTU decreases the thymulin serum levels and the number of cells containing the hormone. These findings suggest that thyroid hormones stimulate the synthesis and secretion of thymulin and represent further evidence for the hormonal influence on the regulation of thymic endocrine secretion.

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Year:  1984        PMID： 6584256      PMCID： PMC1535945     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  17 in total

1.  Isolation, biochemical characteristics, and biological activity of a circulating thymic hormone in the mouse and in the human.

Authors:  J F Bach; M Dardenne; J M Pleau; M A Bach
Journal:  Ann N Y Acad Sci       Date:  1975-02-28       Impact factor: 5.691

2.  The isolation of thymopoietin (thymin).

Authors:  G Goldstein
Journal:  Ann N Y Acad Sci       Date:  1975-02-28       Impact factor: 5.691

3.  Epithelial cell proliferation in thymic hyperplasia induced by triiodothyronine.

Authors:  J M Scheiff; A C Cordier; S Haumont
Journal:  Clin Exp Immunol       Date:  1977-03       Impact factor: 4.330

4.  Cytoplasmic localization of FTS (facteur thymique sérique) in thymic epithelial cells. An immunoelectronmicroscopical study.

Authors:  D Schmitt; J C Monier; M Dardenne; J M Pleau; P Deschaux; J F Bach
Journal:  Thymus       Date:  1980-12

5.  [In vitro regulation of the secretion of thymulin (STF) by human thymic epithelial cells].

Authors:  S Cohen; S Berrih; M Dardenne; J F Bach
Journal:  C R Seances Acad Sci III       Date:  1983

6.  High affinity binding sites on plasma membrane obtained from the lymphoblastoid cultured 1301 cell line for highly radioactive serum thymic factor.

Authors:  L N Gastinel; J M Pleau; M Dardenne; A Sasaki; E Bricas; J L Morgat; J F Bach
Journal:  Biochim Biophys Acta       Date:  1982-01-04

7.  Thymic hormone containing cells. III. Evidence for a feed-back regulation of the secretion of the serum thymic factor (FTS) by thymic epithelial cells.

Authors:  W Savino; M Dardenne; J F Bach
Journal:  Clin Exp Immunol       Date:  1983-04       Impact factor: 4.330

8.  Specific receptors for the serum thymic factor (FTS) in lymphoblastoid cultured cell lines.

Authors:  J M Pléau; V Fuentes; J L Morgat; J F Bach
Journal:  Proc Natl Acad Sci U S A       Date:  1980-05       Impact factor: 11.205

9.  Characterization of facteur thymique sérique (FTS) in the thymus. I. Fixation of anti-FTS antibodies on thymic reticulo-epithelial cells.

Authors:  J C Monier; M Dardenne; J M Pléau; D Schmitt; P Deschaux; J F Bach
Journal:  Clin Exp Immunol       Date:  1980-12       Impact factor: 4.330

10.  Immunohistologic localization of "facteur thymique serique" (FTS) in human thymic epithelium.

Authors:  B Jambon; P Montagne; M C Bene; M P Brayer; G Faure; J Duheille
Journal:  J Immunol       Date:  1981-11       Impact factor: 5.422
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  5 in total

1.  Thymulin-based gene therapy and pituitary function in animal models of aging.

Authors:  Paula C Reggiani; Brenda Poch; Gloria M Cónsole; Omar J Rimoldi; Jose I Schwerdt; Victoria Tüngler; Margarita M Garcia-Bravo; Mireille Dardenne; Rodolfo G Goya
Journal:  Neuroimmunomodulation       Date:  2011-09-22       Impact factor: 2.492

Review 2.  Functional anatomy of the thymic microenvironment.

Authors:  M D Kendall
Journal:  J Anat       Date:  1991-08       Impact factor: 2.610

3.  Neuroendocrine-thymus interactions. I. In vitro modulation of thymic factor secretion by thyroid hormones.

Authors:  E Mocchegiani; L Amadio; N Fabris
Journal:  J Endocrinol Invest       Date:  1990-02       Impact factor: 4.256

Review 4.  The thymus-neuroendocrine axis: physiology, molecular biology, and therapeutic potential of the thymic peptide thymulin.

Authors:  Paula C Reggiani; Gustavo R Morel; Gloria M Cónsole; Claudio G Barbeito; Silvia S Rodriguez; Oscar A Brown; Maria Jose Bellini; Jean-Marie Pléau; Mireille Dardenne; Rodolfo G Goya
Journal:  Ann N Y Acad Sci       Date:  2009-02       Impact factor: 5.691

Review 5.  Dynamic Interactions Between the Immune System and the Neuroendocrine System in Health and Disease.

Authors:  John R Klein
Journal:  Front Endocrinol (Lausanne)       Date:  2021-03-22       Impact factor: 5.555
  5 in total

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