Literature DB >> 6583454

Antitumoral activity of indomethacin on experimental esophageal tumors.

C A Rubio.   

Abstract

The effect of treatment with indomethacin on diethylnitrosamine (DENA, CAS:55-18-5; N-nitrosodiethylamine)-induced esophageal tumors was investigated in 128 C57BL mice. The number of DENA-induced esophageal tumors was significantly reduced when indomethacin was given together with DENA from the outset, suggesting that indomethacin may prevent the induction of esophageal tumors in the C57BL mouse. Similarly, esophageal tumors were significantly reduced when indomethacin was given 4 months after DENA treatment, suggesting that the delayed indomethacin administration may inhibit the further appearance of additional esophageal tumors in the C57BL mouse.

Entities:  

Mesh：

Substances：

Year:  1984        PMID： 6583454

Source DB:  PubMed          Journal:  J Natl Cancer Inst        ISSN： 0027-8874            Impact factor:   13.506


  10 in total

1.  Inhibition of tumor metastasis by carrageenan-induced granulomas.

Authors:  W J Kort; A M Bijma; I M Hekking
Journal:  Clin Exp Metastasis       Date:  1989 Jan-Feb       Impact factor: 5.150

2.  Tumouricidal effect of indomethacin in the esophagus.

Authors:  G P Morgan; J G Williams
Journal:  Postgrad Med J       Date:  1993-12       Impact factor: 2.401

Review 3.  [Epidemiological studies for evaluating the role of cyclooxygenase in chemoprevention of malignant tumors].

Authors:  Eva S Schernhammer; Christian Dittrich
Journal:  Wien Med Wochenschr       Date:  2003

4.  Cyclooxygenase-2 expression in Barrett's esophagus.

Authors:  H M Kandil; G Tanner; W Smalley; S Halter; A Radhika; R N Dubois
Journal:  Dig Dis Sci       Date:  2001-04       Impact factor: 3.199

5.  Expression of cyclooxygenase-2 in human esophageal squamous cell carcinomas.

Authors:  Jian-Gang Jiang; Jiang-Bo Tang; Chun-Lian Chen; Bao-Xing Liu; Xiang-Ning Fu; Zhi-Hui Zhu; Wei Qu; Katherine Cianflone; Michael-P Waalkes; Dao-Wen Wang
Journal:  World J Gastroenterol       Date:  2004-08-01       Impact factor: 5.742

6.  Reduced 15S-lipoxygenase-2 expression in esophageal cancer specimens and cells and upregulation in vitro by the cyclooxygenase-2 inhibitor, NS398.

Authors:  Xiao-Chun Xu; Scott B Shappell; Zhengdong Liang; Shumei Song; David Menter; Vemparala Subbarayan; Sunita Iyengar; Dean G Tang; Scott M Lippman
Journal:  Neoplasia       Date:  2003 Mar-Apr       Impact factor: 5.715

7.  Anti-inflammation induced by counter-irritation or by treatment with non-steroidal agents inhibits the growth of a tumour of non-detected immunogenicity.

Authors:  D O Sordelli; P A Fontán; R P Meiss; R A Ruggiero; O D Bustuoabad
Journal:  Br J Cancer       Date:  1989-11       Impact factor: 7.640

8.  Decrease of prostaglandin E2 and 5-bromo-2'-deoxyuridine labeling but not prostate tumor development by indomethacin treatment of rats given 3,2'-dimethyl-4-aminobiphenyl and testosterone propionate.

Authors:  M Kawabe; M A Shibata; M Sano; Y Takesada; S Tamano; N Ito; T Shirai
Journal:  Jpn J Cancer Res       Date:  1997-04

9.  The Cytotoxicity and Synergistic Potential of Aspirin and Aspirin Analogues Towards Oesophageal and Colorectal Cancer.

Authors:  Rajagopal S Kilari; Asma'u I J Bashir; Andreue Devitt; Christopher J Perry; Stephen T Safrany; Iain D Nicholl
Journal:  Curr Clin Pharmacol       Date:  2019

10.  Validity of short-term examination for antipromoters of bladder carcinogenesis.

Authors:  T Kakizoe; K Takai; K Tobisu; M Ohtani; S Sato
Journal:  Jpn J Cancer Res       Date:  1988-02
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.