Literature DB >> 658316

Neuromuscular junction blocking agents: an initial screening bioassay.

A Sajdak, N Shaath.   

Abstract

A simple, rapid and sensitive in vivo bioassay for the initial screening of neuromuscular junction (NMJ) blocking agents has been accomplished. The i.v. retro-orbital plexus (IVROP) mode of injection was utilized, for the first time, in conjunction with the mouse inclined screen bioassay.

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Year:  1978        PMID： 658316     DOI： 10.1007/BF01947350

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  4 in total

1.  Sterochemical preferences for curarimimetic neuromuscular junction blockade III: enantiomeric bisquaternary amines related to benzoquinonium as probes.

Authors:  T O Soine; W A Hanley; N A Shaath; A A Genenah
Journal:  J Pharm Sci       Date:  1975-01       Impact factor: 3.534

2.  The effect of structural variation in the quaternary nitrogen centers of benzoquinonium chloride upon neuromuscular blocking activity.

Authors:  J O HOPPE; J E FUNNELL; H LAPE
Journal:  J Pharmacol Exp Ther       Date:  1955-09       Impact factor: 4.030

3.  The assay of curare by the rabbit head-drop method.

Authors:  R F VARNEY; C R LINEGAR; H A HOLADAY
Journal:  J Pharmacol Exp Ther       Date:  1949-09       Impact factor: 4.030

4.  A pharmacological investigation of 2,5-bis-(3-diethylaminopropylamino) benzoquinone-bis-benzylchloride (WIN 2747): a new curarimimetic drug.

Authors:  J O HOPPE
Journal:  J Pharmacol Exp Ther       Date:  1950-11       Impact factor: 4.030
  4 in total

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