Literature DB >> 658308

Long-term depression of two primary immune responses induced by a single dose of 5-(3,3-dimethyl-1-triazeno)-imidazole-4-carboxamide (DTIC).

P Puccetti, A Giampietri, M C Fioretti.   

Abstract

2 primary immune responses (anti-SRBC antibody response and allograft rejection) have been tested in mice at various time intervals after single doses of either DTIC or cyclophosphamide. The DTIC-induced immunodepression proved to be extremely long-lasting, being still detectable after 2 months.

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Year:  1978        PMID： 658308     DOI： 10.1007/BF01947335

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  8 in total

Review 1.  Plaque forming cells: methodology and theory.

Authors:  N K Jerne; C Henry; A A Nordin; H Fuji; A M Koros; I Lefkovits
Journal:  Transplant Rev       Date:  1974

2.  Antigenic changes of L1210 leukemia in mice treated with 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide.

Authors:  E Bonmassar; A Bonmassar; S Vadlamudi; A Goldin
Journal:  Cancer Res       Date:  1972-07       Impact factor: 12.701

3.  Cellular immune response to a drug-treated L5178Y lymphoma subline.

Authors:  A Nicolin; A Bini; E Coronetti; A Goldin
Journal:  Nature       Date:  1974-10-18       Impact factor: 49.962

4.  Preliminary clinical trial and the physiologic disposition of 4(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide in man.

Authors:  J L Skibba; G Ramirez; D D Beal; G T Bryan
Journal:  Cancer Res       Date:  1969-11       Impact factor: 12.701

5.  Some pharmacokinetic aspects of 5-(dimethylriazeno)-imidazole-4-carboxamide in the dog.

Authors:  T L Loo; B B Tanner; G E Housholder; B J Shepard
Journal:  J Pharm Sci       Date:  1968-12       Impact factor: 3.534

6.  Increased immunogenicity of two lymphoma lines after drug treatment of athymic (nude) mice.

Authors:  F Campanile; D P Houchens; M Gaston; A Goldin; E Bonmassar
Journal:  J Natl Cancer Inst       Date:  1975-07       Impact factor: 13.506

7.  The immunodepressive and hematotoxic activity of imidazole-4-carboxamide,5-(3,3-dimethyl-1-triazeno) in mice.

Authors:  A Vecchi; M C Fioretti; A Mantovani; A Barzi; F Spreafico
Journal:  Transplantation       Date:  1976-12       Impact factor: 4.939

8.  Immunological alteration of leukemic cells in vivo after treatment with an antitumor drug.

Authors:  E Bonmassar; A Bonmassar; S Vadlamudi; A Goldin
Journal:  Proc Natl Acad Sci U S A       Date:  1970-08       Impact factor: 11.205
  8 in total
  4 in total

1.  Chemical xenogenization of murine lymphoma cells with triazene derivatives: immunotoxicological studies.

Authors:  B Nardelli; P Puccetti; L Romani; G Sava; E Bonmassar; M C Fioretti
Journal:  Cancer Immunol Immunother       Date:  1984       Impact factor: 6.968

Review 2.  Chemical xenogenization of experimental tumors.

Authors:  P Puccetti; L Romani; M C Fioretti
Journal:  Cancer Metastasis Rev       Date:  1987       Impact factor: 9.264

3.  Effects of prolonged treatment with decarbazine on tumor metastatic potential in mice bearing Lewis lung carcinoma.

Authors:  S Zorzet; L Perissin; V Rapozzi; S Pacor; T Giraldi
Journal:  Clin Exp Metastasis       Date:  1995-03       Impact factor: 5.150

4.  Two antiemetic regimens do not impair chemical xenogenization induced in vivo by 5-(3,3-dimethyl-1-triazeno)-imidazole-4-carboxamide.

Authors:  P Ballerini; A Franchi; P Fuschiotti; D Piccioni; E Bonmassar
Journal:  Cancer Chemother Pharmacol       Date:  1989       Impact factor: 3.333
  4 in total

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