Literature DB >> 6583027

Modification of oral methotrexate absorption in children with leukemia.

M J Mahony, M S Murphy, J Wadsworth, M G Mott.   

Abstract

The effect of administering oral methotrexate in different formulations to children with acute lymphoblastic leukemia was evaluated. Methotrexate tablets alone achieved higher mean plasma levels and larger area under the absorption curve than either methotrexate liquid alone or methotrexate tablets taken concurrently with metoclopramide.

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Year:  1984        PMID: 6583027     DOI: 10.1007/bf00254605

Source DB:  PubMed          Journal:  Cancer Chemother Pharmacol        ISSN: 0344-5704            Impact factor:   3.333


  5 in total

1.  Unpredictable serum levels after oral methotrexate in children with acute lymphoblastic leukaemia.

Authors:  P J Kearney; P A Light; A Preece; M G Mott
Journal:  Cancer Chemother Pharmacol       Date:  1979       Impact factor: 3.333

2.  Methotrexate-induced malabsorption in children with acute lymphoblastic leukaemia.

Authors:  A W Craft; H Kay; D N Lawson; T J McElwain
Journal:  Br Med J       Date:  1977-12-10

3.  Methotrexate absorption in children with acute lymphoblastic leukemia.

Authors:  A W Craft; A Rankin; W Aherne
Journal:  Cancer Treat Rep       Date:  1981

4.  Can food influence the absorption of methotrexate in children with acute lymphoblastic leukaemia?

Authors:  C R Pinkerton; S G Welshman; J F Glasgow; J M Bridges
Journal:  Lancet       Date:  1980-11-01       Impact factor: 79.321

5.  Serum profiles of methotrexate after its administration in children with acute lymphoblastic leukaemia.

Authors:  C R Pinkerton; S G Welshman; J M Bridges
Journal:  Br J Cancer       Date:  1982-02       Impact factor: 7.640

  5 in total
  1 in total

Review 1.  Pharmacokinetic drug interactions with gastrointestinal motility modifying agents.

Authors:  J M Greiff; D Rowbotham
Journal:  Clin Pharmacokinet       Date:  1994-12       Impact factor: 6.447

  1 in total

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