Literature DB >> 658302

Lipid accumulation in mouse hepatocytes after morphine exposure.

A Thureson-Klein, J Wang-Yang, I K Ho.   

Abstract

After morphine injection lipid accumulation in mouse hepatocytes begins within 2 h and continues for 24 h when most hepatocytes are filled with lipid droplets. In spite of morphine maintenance the liver recovers as the accumulated lipids are coupled with protein and subsequently transported and released into the perisinusoidal space of Disse.

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Year:  1978        PMID： 658302     DOI： 10.1007/BF01947319

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  11 in total

1.  Some effects of morphine on lipid metabolism in normal, tolerant and abstinent rats.

Authors:  R Sablé-Amplis; R Agid; D Abadie
Journal:  Life Sci       Date:  1975-05-01       Impact factor: 5.037

2.  Effect of fasting, epinephrine and glucose and insulin on hepatic uptake of nonesterified fatty acids.

Authors:  M B FINE; R H WILLIAMS
Journal:  Am J Physiol       Date:  1960-09

3.  The carbohydrate constituents of human serum beta-lipoprotein: galactose, mannose, glucosamine and sialic acid.

Authors:  W E MARSHALL; F A KUMMEROW
Journal:  Arch Biochem Biophys       Date:  1962-08       Impact factor: 4.013

4.  Morphine and the incorporation of 32-orthophosphate in vivo into phospholipids of the guinea pig cerebral cortex, liver and subcellular fractions.

Authors:  S J Mulé
Journal:  Biochem Pharmacol       Date:  1970-02       Impact factor: 5.858

5.  Morphine and the incorporation of Pi32 into brain phospholipids of nontolerant, tolerant and abstinent guinea pigs.

Authors:  S J Mulé
Journal:  J Pharmacol Exp Ther       Date:  1967-04       Impact factor: 4.030

6.  Hepatic lipid metabolism in experimental diabetes. V. The effect of concentration of oleate on metabolism of triglycerides and on ketogenesis.

Authors:  D R Van Harken; C W Dixon; M Heimberg
Journal:  J Biol Chem       Date:  1969-05-10       Impact factor: 5.157

7.  Simultaneous quantitative assessment of morphine tolerance and physical dependence.

Authors:  E L Way; H H Loh; F H Shen
Journal:  J Pharmacol Exp Ther       Date:  1969-05       Impact factor: 4.030

8.  Effect of prolonged morphine administration on certain histochemical reactions in rat liver.

Authors:  Z Myca
Journal:  Pol Med J       Date:  1967

9.  Electron microscopic and biochemical study of lipoprotein synthesis in the isolated perfused rat liver.

Authors:  A L Jones; N B Ruderman; M G Herrera
Journal:  J Lipid Res       Date:  1967-09       Impact factor: 5.922

10.  A FINE STRUCTURE STUDY OF LIPID IN MOUSE LIVER REGENERATING AFTER PARTIAL HEPATECTOMY.

Authors:  N L TROTTER
Journal:  J Cell Biol       Date:  1964-05       Impact factor: 10.539
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  3 in total

1.  Lack of hepatocyte involvement in the genesis of the sinusoidal dilatation related to heroin addiction: a morphometric study.

Authors:  M S Trigueiro de Araújo; F Gérard; P Chossegros; S Guerret; J A Grimaud
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1992

2.  Stimulation of lipid peroxidation and impairment of glutathione-dependent defense system in Wistar rats treated with cryptopine, a rare non-narcotic opium alkaloid.

Authors:  Ritu Aneja; Anju Katyal; Ramesh Chandra
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2004 Jan-Mar       Impact factor: 2.441

3.  Histopathological study of liver tissue due to methadone consumption and its effect on liver enzymes and inflammatory indices in rat.

Authors:  Mansour Amraei; Mahmoud Mohamadpour; Mohammad Reza Hafezi Ahmadi; Monireh Azizi; Ahmad Daemi; Mohammad Omidi; Ehsan Shirzadpour
Journal:  Drug Des Devel Ther       Date:  2018-11-05       Impact factor: 4.162
  3 in total

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