Literature DB >> 658263

Fluorescence microscopical study of 5-hydroxytryptamine storage organelles in mepacrine-incubated blood platelets of beige mice (Chediak-Higashi syndrome).

H P Lorez, M Da Prada.   

Abstract

The number and fluorescence intensity of fluorescent granules (5-HT storage organelles) of mepacrine-incubated blood platelets of beige mice (Chediak-Higashi syndrome) are decreased compared to those of control mice platelets. This indicates both quantitative and qualitative changes of the 5-HT organelles, namely a reduced number and a reduced storage capacity, respectively.

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Year:  1978        PMID： 658263     DOI： 10.1007/BF01937020

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  16 in total

1.  Identification and assay of serotonin in brain.

Authors:  D F BOGDANSKI; A PLETSCHER; B B BRODIE; S UNDENFRIEND
Journal:  J Pharmacol Exp Ther       Date:  1956-05       Impact factor: 4.030

2.  Accumulation of basic drugs in 5-hydroxytryptamine storage organelles of rabbit blood platelets.

Authors:  M Da Prada; A Pletscher
Journal:  Eur J Pharmacol       Date:  1975 Jun-Jul       Impact factor: 4.432

3.  The Chediak-Higashi syndrome.

Authors:  A R PAGE; H BERENDES; J WARNER; R A GOOD
Journal:  Blood       Date:  1962-09       Impact factor: 22.113

4.  Granulocyte function in the Chediak-Higashi syndrome of mice.

Authors:  J I Gallin; J S Bujak; E Patten; S M Wolff
Journal:  Blood       Date:  1974-02       Impact factor: 22.113

5.  The Chediak-Higashi syndrome: studies in four patients and a review of the literature.

Authors:  R S Blume; S M Wolff
Journal:  Medicine (Baltimore)       Date:  1972-07       Impact factor: 1.889

6.  Giant granules in leukocytes of the beige mouse.

Authors:  M A Lutzner; C T Lowrie; H W Jordan
Journal:  J Hered       Date:  1967 Nov-Dec       Impact factor: 2.645

7.  Serotonin deficiency and prolonged bleeding in beige mice.

Authors:  J M Holland
Journal:  Proc Soc Exp Biol Med       Date:  1976-01

8.  Localization of platelet prostaglandin production in the platelet dense tubular system.

Authors:  J M Gerrard; J G White; G H Rao; D Townsend
Journal:  Am J Pathol       Date:  1976-05       Impact factor: 4.307

9.  Uranaffin reaction: a new cytochemical technique for the localization of adenine nucleotides in organelles storing biogenic amines.

Authors:  J G Richards; M Da Prada
Journal:  J Histochem Cytochem       Date:  1977-12       Impact factor: 2.479

10.  Mepacrine, a tool for investigating the 5-hydroxytryptamine organelles of blood platelets by fluorescence microscopy.

Authors:  H P Lorez; M Da Prada; F Rendu; A Pletscher
Journal:  J Lab Clin Med       Date:  1977-01
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  5 in total

Review 1.  Molecular defects that affect platelet dense granules.

Authors:  Meral Gunay-Aygun; Marjan Huizing; William A Gahl
Journal:  Semin Thromb Hemost       Date:  2004-10       Impact factor: 4.180

2.  Enlarged dysmorphic lysosomes in an established beige (C57BL/6J;bgJ(/bgJ)) mouse mutant fibroblast line: a reversible characteristic.

Authors:  J B Gow; T A Lyerla; S Lainwala
Journal:  In Vitro Cell Dev Biol Anim       Date:  1996-09       Impact factor: 2.416

3.  Cellular expression of the beige mouse mutation and its correction in hybrids with control human fibroblasts.

Authors:  J B Gow; S Lainwala; T A Lyerla
Journal:  In Vitro Cell Dev Biol Anim       Date:  1993-11       Impact factor: 2.416

4.  Platelet dense granules begin to selectively accumulate mepacrine during proplatelet formation.

Authors:  Hayley A Hanby; Jialing Bao; Ji-Yoon Noh; Danuta Jarocha; Mortimer Poncz; Mitchell J Weiss; Michael S Marks
Journal:  Blood Adv       Date:  2017-08-22

5.  Evidence that abnormal platelet functions in human Chédiak-Higashi syndrome are the result of a lack of dense bodies.

Authors:  F Rendu; J Breton-Gorius; M Lebret; C Klebanoff; D Buriot; C Griscelli; S Levy-Toledano; J P Caen
Journal:  Am J Pathol       Date:  1983-06       Impact factor: 4.307
  5 in total

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