Literature DB >> 658256

Cytostatic activity of organic compounds and their average quasi-valence number.

V Veljković, V Ajdacić.   

Abstract

It is found that the average quasi-valence numbers of alkylating cytostatics lie in the region of potential carcinogens, while the average quasi-valence numbers of antimetabolites predominantly cover the region of noncarcinogens. Implications of this finding on the design of new drugs are discussed.

Mesh：

Substances：

Year:  1978        PMID： 658256     DOI： 10.1007/BF01937008

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  2 in total

1.  Theoretical prediction of mutagenicity and carcinogenicity of chemical substances.

Authors:  V J Veljkovic; D I Lalovic
Journal:  Cancer Biochem Biophys       Date:  1976

2.  Simple theoretical criterion of chemical carcinogenicity.

Authors:  V Veljković; D I Lalović
Journal:  Experientia       Date:  1977-09-15
  2 in total
  2 in total

1.  Simple theoretical criterion of chemical carcinogenicity - a refutation.

Authors:  D H Rosenblatt; J C Dacre
Journal:  Experientia       Date:  1979-04-15

2.  Antibiotic activity of organic compounds and their average quasi-valence number.

Authors:  V Ajdacić; V Veljković
Journal:  Experientia       Date:  1978-05-15
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.