Literature DB >> 658243

The effect of bradykinin on the electrical activity of rat jejunum.

J Hardcastle, P T Hardcastle, R J Flower, P A Sanford.   

Abstract

Bradykinin increased the potential difference across both the jejunum and colon of the rat. This effect was significantly reduced by indomethacin, suggesting that it was mediated by prostaglandins. The possibility that bradykinin may contribute to the diarrhoea of the carcinoid syndrome by inducing a net secretory state in the intestine is discussed.

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Year:  1978        PMID： 658243     DOI： 10.1007/BF01936993

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  13 in total

1.  Release of additional factors in anaphylaxis and its antagonism by anti-inflammatory drugs.

Authors:  P J Piper; J R Vane
Journal:  Nature       Date:  1969-07-05       Impact factor: 49.962

Review 2.  The release and fate of vaso-active hormones in the circulation.

Authors:  J R Vane
Journal:  Br J Pharmacol       Date:  1969-02       Impact factor: 8.739

3.  Proceedings: Prostaglandins and intestinal function.

Authors:  J Eggenton; R J Flower; P T Hardcastle; P A Sanford; D H Smyth
Journal:  J Physiol       Date:  1974-04       Impact factor: 5.182

4.  The effect of bradykinin on intestinal motility and blood flow.

Authors:  S Fasth; L Hultén
Journal:  Acta Chir Scand       Date:  1973

5.  Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs.

Authors:  J R Vane
Journal:  Nat New Biol       Date:  1971-06-23

6.  Jejunal fluid and electrolyte secretion in carcinoid syndrome.

Authors:  M Donowitz; H J Binder
Journal:  Am J Dig Dis       Date:  1975-12

Review 7.  Kinins in human disease.

Authors:  D L Wilhelm
Journal:  Annu Rev Med       Date:  1971       Impact factor: 13.739

8.  Effect of bradykinin on transepithelial transfer of sodium and water in vitro.

Authors:  A D Crocker; S P Willavoys
Journal:  J Physiol       Date:  1975-12       Impact factor: 5.182

9.  Ionic conductances of extracellular shunt pathway in rabbit ileum. Influence of shunt on transmural sodium transport and electrical potential differences.

Authors:  R A Frizzell; S G Schultz
Journal:  J Gen Physiol       Date:  1972-03       Impact factor: 4.086

10.  Stimulation of intestinal mucosal adenyl cyclase by cholera enterotoxin and prostaglandins.

Authors:  D V Kimberg; M Field; J Johnson; A Henderson; E Gershon
Journal:  J Clin Invest       Date:  1971-06       Impact factor: 14.808
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  2 in total

1.  Kinins stimulate net chloride secretion by the rat colon.

Authors:  A W Cuthbert; H S Margolius
Journal:  Br J Pharmacol       Date:  1982-04       Impact factor: 8.739

2.  The secretory actions of histamine in rat small intestine.

Authors:  J Hardcastle; P T Hardcastle
Journal:  J Physiol       Date:  1987-07       Impact factor: 5.182
  2 in total

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