Literature DB >> 658230

Depression by ethionine of phosphorylating oxidation in hepatic mitochondria.

E S Higgins, W H Friend, K S Rogers.   

Abstract

Induction of hepatic steatosis and suppression of hepatic ATP levels, protein synthesis and gluconeogenesis subsequent to administration of ethionine may be consequences of interference by this compound with mitochondrial phosphorylation of ADP. The mitochondrial dysfunction is not a direct action of ethionine on the organelle.

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Year:  1978        PMID: 658230     DOI: 10.1007/BF01936969

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  16 in total

Review 1.  BIOCHEMICAL PATHOLOGY OF ACUTE HEPATIC ADENOSINETRIPHOSPHATE DEFICIENCY.

Authors:  E FARBER; K H SHULL; S VILLA-TREVINO; B LOMBARDI; M THOMAS
Journal:  Nature       Date:  1964-07-04       Impact factor: 49.962

Review 2.  ETHIONINE CARCINOGENESIS.

Authors:  E FARBER
Journal:  Adv Cancer Res       Date:  1963       Impact factor: 6.242

3.  THE PREVENTION BY ADENOSINE TRIPHOSPHATE OF THE FATTY LIVER INDUCED BY ETHIONINE.

Authors:  E FARBER; B LOMBARDI; A E CASTILLO
Journal:  Lab Invest       Date:  1963-09       Impact factor: 5.662

Review 4.  BIOCHEMICAL BASIS FOR ETHIONINE EFFECTS ON TISSUES.

Authors:  J A STEKOL
Journal:  Adv Enzymol Relat Subj Biochem       Date:  1963

5.  The respiratory chain and oxidative phosphorylation.

Authors:  B CHANCE; G R WILLIAMS
Journal:  Adv Enzymol Relat Subj Biochem       Date:  1956

6.  Cognate effects of ethanol, hydrazine and tissue regeneration on heaptic mitochondrial activities.

Authors:  E S Higgins; W L Banks
Journal:  Biochem Pharmacol       Date:  1971-07       Impact factor: 5.858

7.  Time course of the acute alcoholic fatty liver and concomitant mitochondrial function in fasted rats.

Authors:  E S Higgins; W H Friend
Journal:  Proc Soc Exp Biol Med       Date:  1972-12

8.  The effect of ethionine on metabolism of adenosine triphosphate.

Authors:  L Kotite; H Tarver
Journal:  Proc Soc Exp Biol Med       Date:  1969-06

9.  On the mechanism of induction of hepatic adenosine triphosphate deficiency by ethionine.

Authors:  K H Shull; J McConomy; M Vogt; A Castillo; E Farber
Journal:  J Biol Chem       Date:  1966-11-10       Impact factor: 5.157

10.  Evidence for ethylation of rat liver deoxyribonucleic acid after administration of ethionine.

Authors:  P F Swann; A E Pegg; A Hawks; E Farber; P N Magee
Journal:  Biochem J       Date:  1971-06       Impact factor: 3.857

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  3 in total

1.  Effect of ethionine on hepatic mitochondrial and microsomal calcium uptake.

Authors:  A K Agarwal; W D Zinermon; L Latoni
Journal:  Bull Environ Contam Toxicol       Date:  1988-02       Impact factor: 2.151

2.  2-Mercaptoacetate administration depresses the beta-oxidation pathway through an inhibition of long-chain acyl-CoA dehydrogenase activity.

Authors:  F Bauché; D Sabourault; Y Giudicelli; J Nordmann; R Nordmann
Journal:  Biochem J       Date:  1981-06-15       Impact factor: 3.857

3.  Effects of 2-mercaptoacetate in isolated liver mitochondria in vitro. Competitive inhibition of 3-hydroxybutyrate dehydrogenase and depression of the beta-oxidation pathway.

Authors:  F Bauché; D Sabourault; Y Giudicelli; J Nordmann; R Nordmann
Journal:  Biochem J       Date:  1982-07-15       Impact factor: 3.857

  3 in total

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