Literature DB >> 65791

Neurophysin biosynthesis: conversion of a putative precursor during axonal transport.

H Gainer, Y Sarne, M J Brownstein.   

Abstract

[35S]Cysteine injected adjacent to the supraoptic nucleus of the rat is rapidly incorporated into a 20,000-dalton protein that, in time, is converted to a 12,000-dalton labeled protein, neurophysin. This putative precursor of neurophysin appears to be synthesized in the supraoptic nucleus and transformed to neurophysin and related peptides during axonal transport to the neurohypophysis.

Entities:  

Mesh：

Substances：

Year:  1977        PMID： 65791     DOI： 10.1126/science.65791

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  20 in total

Review 1.  Molecular diversity in neurosecretion: reflections on the hypothalamo-neurohypophysial system.

Authors:  H Gainer; H Chin
Journal:  Cell Mol Neurobiol       Date:  1998-04       Impact factor: 5.046

Review 2.  Cell-type specific expression of oxytocin and vasopressin genes: an experimental odyssey.

Authors:  H Gainer
Journal:  J Neuroendocrinol       Date:  2012-04       Impact factor: 3.627

3.  Squid Giant Axon Contains Neurofilament Protein mRNA but does not Synthesize Neurofilament Proteins.

Authors:  Harold Gainer; Shirley House; Dong Sun Kim; Hemin Chin; Harish C Pant
Journal:  Cell Mol Neurobiol       Date:  2016-05-20       Impact factor: 5.046

Review 4.  Protein-hormonal complexes of the hypothalamus as neurochemical systems of regulation.

Authors:  A Galoyan; R Srapionian
Journal:  Neurochem Res       Date:  1983-12       Impact factor: 3.996

5.  Prosomatostatin-specific antigen in rat brain: localization by immunocytochemical staining with an antiserum to a synthetic sequence of preprosomatostatin.

Authors:  R M Lechan; R H Goodman; M Rosenblatt; S Reichlin; J F Habener
Journal:  Proc Natl Acad Sci U S A       Date:  1983-05       Impact factor: 11.205

Review 6.  Hormonal and local regulation of uterine activity during parturition: Part I--The oxytocin system.

Authors:  M Maggi; E Baldi; T Susini
Journal:  J Endocrinol Invest       Date:  1994-10       Impact factor: 4.256

7.  Two different Na,K-ATPases in the optic nerve: cells of origin and axonal transport.

Authors:  S C Specht; K J Sweadner
Journal:  Proc Natl Acad Sci U S A       Date:  1984-02       Impact factor: 11.205

8.  Nature of the immunoreactive neurophysins in ectopic vasopressin-producing oat cell carcinomas of the lung. Demonstration of a putative common precursor to vasopressin and neurophysin.

Authors:  T Yamaji; M Ishibashi; S Katayama
Journal:  J Clin Invest       Date:  1981-08       Impact factor: 14.808

9.  Trypsin liberates an arginine vasopressin-like peptide and neurophysin from a Mr 20,000 putative common precursor.

Authors:  J T Russell; M J Brownstein; H Gainer
Journal:  Proc Natl Acad Sci U S A       Date:  1979-12       Impact factor: 11.205

10.  Membrane retrieval in the guinea-pig neurohypophysis. Isolation and characterization of secretory vesicles and coated microvesicles after radiolabel incorporation in vivo.

Authors:  T Saermark; P M Jones; I C Robinson
Journal:  Biochem J       Date:  1984-03-01       Impact factor: 3.857
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.