Literature DB >> 65786

Hematoporphyrin-sensitized photodynamic inactivation of viral RNA-dependent DNA polymerase.

B R Munson, R J Fiel.   

Abstract

Visible light (6328A) was shown to inactivate RNA-dependent DNA polymerase activity of Moloney mouse leukemia virus, in the presence of hematoporphyrin. The same treatment on exogenous, template-initiation complex had no effect on enzyme activity. It was suggested that this enzyme may be the target of photodynamic inactivation of this and related viruses.

Entities:  

Mesh:

Substances:

Year:  1977        PMID: 65786

Source DB:  PubMed          Journal:  Res Commun Chem Pathol Pharmacol        ISSN: 0034-5164


  2 in total

1.  Photodynamic effects of haematoporphyrin derivative on DNA repair in murine L929 fibroblasts.

Authors:  J P Boegheim; T M Dubbelman; L H Mullenders; J Van Steveninck
Journal:  Biochem J       Date:  1987-06-15       Impact factor: 3.857

2.  A SARS-CoV-2 cytopathicity dataset generated by high-content screening of a large drug repurposing collection.

Authors:  Bernhard Ellinger; Denisa Bojkova; Andrea Zaliani; Jindrich Cinatl; Carsten Claussen; Sandra Westhaus; Oliver Keminer; Jeanette Reinshagen; Maria Kuzikov; Markus Wolf; Gerd Geisslinger; Philip Gribbon; Sandra Ciesek
Journal:  Sci Data       Date:  2021-02-26       Impact factor: 6.444

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.