Literature DB >> 6578235

A mouthrinse which optimizes in vivo generation of hypothiocyanite.

B Mansson-Rahemtulla, K M Pruitt, J Tenovuo, T M Le.   

Abstract

We report here the properties of a mouthrinse which enhances one of the natural defense factors in human saliva, the salivary peroxidase system. Concentrations of the antimicrobial agent, the hypothiocyanite (OSCN-) ion, can be increased in vivo to bacteriostatic levels by use of a mouthrinse which is 4 mM (0.014%) in hydrogen peroxide and 1 mM (0.0097%) in potassium thiocyanate at pH 5.5. The volume of the rinse, the H2O2 concentrations, and the pH were shown to be determinants of the concentration of OSCN- generated by the rinse.

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Year:  1983        PMID: 6578235     DOI: 10.1177/00220345830620101101

Source DB:  PubMed          Journal:  J Dent Res        ISSN: 0022-0345            Impact factor:   6.116


  6 in total

1.  Comparison of thiocyanate and selenocyanate for potentiation of antimicrobial photodynamic therapy.

Authors:  Liyi Huang; Weijun Xuan; Tadeusz Sarna; Michael R Hamblin
Journal:  J Biophotonics       Date:  2018-08-03       Impact factor: 3.207

2.  Antibacterial effect of lactoperoxidase and myeloperoxidase against Bacillus cereus.

Authors:  J Tenovuo; K K Mäkinen; G Sievers
Journal:  Antimicrob Agents Chemother       Date:  1985-01       Impact factor: 5.191

3.  In vitro and in vivo studies of cellular lysis of oral bacteria by a lysozyme-protease-inorganic monovalent anion antibacterial system.

Authors:  J J Pollock; J Shoda; T F McNamara; M I Cho; A Campbell; V J Iacono
Journal:  Infect Immun       Date:  1984-09       Impact factor: 3.441

4.  Antibacterial activity of hydrogen peroxide and the lactoperoxidase-hydrogen peroxide-thiocyanate system against oral streptococci.

Authors:  E L Thomas; T W Milligan; R E Joyner; M M Jefferson
Journal:  Infect Immun       Date:  1994-02       Impact factor: 3.441

5.  Oral peroxidases: From antimicrobial agents to ecological actors (Review).

Authors:  Philippe Courtois
Journal:  Mol Med Rep       Date:  2021-05-13       Impact factor: 2.952

6.  Antibacterial and antiplaque efficacy of a lactoperoxidase-thiocyanate-hydrogen-peroxide-system-containing lozenge.

Authors:  A Welk; S Patjek; M Gärtner; R Baguhl; Ch Schwahn; H Below
Journal:  BMC Microbiol       Date:  2021-11-03       Impact factor: 3.605

  6 in total

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